Tiny protein offers major insight into foot-and-mouth virus

Scientists have identified that a tiny protein, which plays a major role in the replication of foot-and-mouth disease virus, demonstrates a greater level of genetic economy than previously reported.

Lead researcher Professor Nicola Stonehouse, from the University of Leeds' Faculty of Biological Sciences, said: "Sometimes it's the little things that can make the big differences. By understanding the role of this tiny viral protein in the replication of foot-and-mouth disease , we're hoping to find more effective vaccines that fight the disease."

Researchers from the University of Leeds and The Pirbright Institute identified a new role for a small viral protein - called 3B3 - revealing how these viruses can copy themselves efficiently. Foot-and-mouth disease is of great economic importance and their findings could lead to the development of more effective vaccines against the in the future.


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Step forward in foot-and-mouth disease understanding

More information: Morgan R. Herod et al, Genetic economy in picornaviruses: Foot-and-mouth disease virus replication exploits alternative precursor cleavage pathways, PLOS Pathogens (2017). DOI: 10.1371/journal.ppat.1006666
Journal information: PLoS Pathogens

Citation: Tiny protein offers major insight into foot-and-mouth virus (2017, October 3) retrieved 22 September 2019 from https://medicalxpress.com/news/2017-10-tiny-protein-major-insight-foot-and-mouth.html
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