MRI-based ovarian morphologic measurements can ID PCOS

November 29, 2017

(HealthDay)—For adolescents with suspicion for polycystic ovary syndrome (PCOS), magnetic resonance (MR) imaging-based ovarian morphologic measurements can help with diagnosis, according to a study published in the December issue of Radiology.

Maxime Fondin, M.D., from INSERM U1018 in Le Kremlin Bicêtre, France, and colleagues matched a case group with high (40 girls with hyperandrogenism and oligomenorrhea or amenorrhea), intermediate (eight girls with hyperandrogenism), and low (seven with oligomenorrhea or amenorrhea) suspicion of PCOS with 55 control subjects with no clinical hyperandrogenism, oligomenorrhea, or .

The researchers observed significant correlations for all criteria except sphericity index and absence of a dominant follicle with the level of suspicion of PCOS. The areas under the receiver operating characteristic curve were significantly greater than 0.5 for the number of follicles per ovary (FPO) measuring 9 mm or smaller (FPO-9), FPO measuring 5 mm or smaller, and ovarian volume (OV), respectively (0.78, 0.73, and 0.77, respectively). Sensitivity and specificity were 33 and 95 percent, respectively, for peripheral distribution of follicles, and 90 and 27 percent, respectively, for absence of a dominant follicle. Reproducibility was highest for OV (intraclass correlation coefficient, 0.89).

"The most accurate MR imaging-based diagnostic criteria for PCOS were OV, FPO-9, and peripheral distribution of follicles; however, reproducibility of these measures was moderate, except that for OV," the authors write.

Explore further: Hirsutism strongly predicts metabolic dysfunction in PCOS

More information: Abstract/Full Text (subscription or payment may be required)

Related Stories

Hirsutism strongly predicts metabolic dysfunction in PCOS

October 2, 2017
(HealthDay)—There is a strong correlation between hirsutism and metabolic dysfunction in women with polycystic ovary syndrome (PCOS), according to a study published online Sept. 21 in the Journal of Cosmetic Dermatology.

Why the definition of polycystic ovary syndrome harms women

August 16, 2017
The changed definition of polycystic ovary syndrome harms women and brings no clear benefit, say Australian scientists in today's British Medical Journal.

Review addresses diagnosis of PCOS in adolescents

November 23, 2015
(HealthDay)—Unexplained persistent hyperandrogenic anovulation can be used to diagnose polycystic ovary syndrome (PCOS) in adolescents, according to a review article published online Nov. 23 in Pediatrics.

New diagnostics for ovarian syndrome

December 5, 2013
(Medical Xpress)—Having multiple ovarian follicles is the leading cause of infertility in America, with wider implications for cancer, cardiovascular disease, metabolic syndromes, hormonal imbalance and mental health. Yet ...

Case vignette addresses diagnosis, management of PCOS

July 7, 2016
(HealthDay)—The diagnosis and management of polycystic ovary syndrome is discussed in a case vignette published online July 6 in The New England Journal of Medicine.

Researchers call for better polycystic ovarian syndrome diagnosis

October 20, 2017
Young women's inconsistent perceptions around their diagnosis of the hormonal condition polycystic ovarian syndrome (PCOS) could be causing them unwarranted concern about their fertility, new research has found.

Recommended for you

Discovery promises improved diagnosis and understanding of endometriosis

March 19, 2018
Feinstein Institute for Medical Research scientists announced an experimental, rapid and non-invasive way to diagnose endometriosis, which may lead to earlier and more effective treatments for this disorder that affects approximately ...

Vaginal estrogen tablets, moisturizers and placebo gel all can improve vaginal discomfort

March 19, 2018
A clinical trial comparing two treatments for postmenopausal vaginal discomfort - low-dose vaginal estrogen and a vaginal moisturizer - to placebo treatments found that both produced symptom improvements similar to those ...

Frozen embryos more successful for conceiving during IVF

March 19, 2018
A new study carried out by a research team at The University of Western Australia and Fertility Specialists of Western Australia has found that women undergoing IVF who have had embryos fail to implant have more success using ...

Alomst 70 percent of 103 genes linked to prenatal death affect the placenta

March 14, 2018
The role of the placenta in healthy fetal development is being seriously under-appreciated according to a new paper published today (14th March). The study was part of the Wellcome Trust-funded "Deciphering the Mechanisms ...

New research shows why babies need to move in the womb

March 12, 2018
Scientists have just discovered why babies need to move in the womb to develop strong bones and joints. It turns out there are some key molecular interactions that are stimulated by movement and which guide the cells and ...

Labour–inducing drugs put to the test

February 27, 2018
Researchers comparing the use of two drugs for pregnant women who do not go into labour shortly after their waters break have found both are reasonable options.


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.