Duration of diabetes, prediabetes linked to presence of CAC

January 12, 2018

(HealthDay)—Diabetes and prediabetes duration are both independently associated with the presence of coronary artery calcified plaque (CAC) and left ventricular dysfunction, according to a study published online Jan. 9 in Diabetes Care.

Jared P. Reis, Ph.D., from the National Heart, Lung, and Blood Institute in Bethesda, Md., and colleagues examined whether the durations of diabetes and prediabetes estimated during a 25-year period in early adulthood are independently associated with CAC. Data were included for 3,628 white and black adults aged 18 to 30 years without diabetes or prediabetes at baseline (1985 to 1986).

The researchers found that 12.7 and 53.8 percent of the participants developed diabetes and prediabetes, respectively, with an average duration of 10.7 and 9.5 years. The hazard ratio for the presence of CAC was 1.15 and 1.07 times higher for each five-years-longer duration of diabetes and prediabetes, respectively, after adjustment for sociodemographic characteristics and other and mutual adjustment for each other. There was a correlation for diabetes and prediabetes duration with worse subclinical systolic function and early diastolic relaxation. There was also a correlation for duration of diabetes with higher diastolic filling pressure.

"Durations of and prediabetes during adulthood are both independently associated with subclinical atherosclerosis and left ventricular systolic and in middle age," the authors write.

Explore further: Economic benefit for lifestyle modification in prediabetes

More information: Abstract/Full Text (subscription or payment may be required)

Related Stories

Economic benefit for lifestyle modification in prediabetes

March 15, 2017
(HealthDay)—For individuals with prediabetes, participation in lifestyle modifications such as the National Diabetes Prevention Program (DPP) is associated with economic benefit, according to a study published online Feb. ...

Estimated prevalence of diabetes among adolescents higher than previously reported

July 19, 2016
In a study appearing in the July 19 issue of JAMA, Andy Menke, Ph.D., of Social & Scientific Systems, Silver Spring, Md., and colleagues estimated the prevalence of diabetes among U.S. adolescents, the percentage of those ...

High prevalence of diabetes, prediabetes in China

June 27, 2017
A large, nationally representative survey in 2013 of adults in China finds that the estimated overall prevalence of diabetes was about 11 percent and that of prediabetes was nearly 36 percent, according to a study published ...

Serum prolactin in pregnancy predicts prediabetes / diabetes

May 2, 2016
(HealthDay)—Serum prolactin in pregnancy predicts the risk of postpartum prediabetes/diabetes, according to a study published online April 26 in Diabetes Care.

Education is essential for optimal diabetes health

November 28, 2017
When you have diabetes, you are certainly not alone. Diabetes is one of the most common chronic conditions affecting over 30 million people in the U.S. About 5 percent of people with diabetes have type 1. Type 2 diabetes ...

Prevalence of metformin use 0.7 percent in prediabetes

April 7, 2017
(HealthDay)—For U.S. adults with prediabetes, the prevalence of metformin use is 0.7 percent, according to a study published online April 3 in Diabetes Care.

Recommended for you

Genomic study brings us closer to precision medicine for type 2 diabetes

September 21, 2018
Most patients diagnosed with type 2 diabetes are treated with a "one-size-fits-all" protocol that is not tailored to each person's physiology and may leave many cases inadequately managed. A new study by scientists at the ...

High gluten diet in pregnancy linked to increased risk of diabetes in children

September 19, 2018
A high gluten intake by mothers during pregnancy is associated with an increased risk of their child developing type 1 diabetes, suggests a study published by The BMJ today.

Anti-inflammatory protein promotes healthy gut bacteria to curb obesity

September 19, 2018
Scientists from the UNC School of Medicine discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet. The researchers also reported ...

Study reveals the current rates of diagnosed type 1 and type 2 diabetes in American adults

September 18, 2018
A new study from the University of Iowa finds that type 2 diabetes remains overwhelmingly the most common type of diabetes diagnosed in American adults who have the disease.

Research reveals link between immunity, diabetes

September 14, 2018
When it comes to diet-induced obesity, your immune system is not always your friend.

BPA exposure in U.S.-approved levels may alter insulin response in non-diabetic adults

September 14, 2018
In a first study of its kind study, researchers have found that a common chemical consumers are exposed to several times a day may be altering insulin release. Results of the study, led by scientists at the University of ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.