Human rhinovirus commonly detected in febrile infants

January 17, 2018

(HealthDay)—For febrile infants, human rhinovirus (HRV) is common, and detection does not alter risk of concomitant urinary tract infection or invasive bacterial infection, according to a study published online Jan. 17 in Pediatrics.

Anne J. Blaschke, M.D., Ph.D., from the University of Utah in Salt Lake City, and colleagues examined the risk of concomitant bacterial infection in febrile infants positive for HRV by (PCR). Infants aged 1 to 90 days who underwent respiratory viral testing by PCR (RVPCR) in the emergency department or inpatient setting were identified. The relative risk of bacterial infection was assessed.

The researchers found that 37 percent of 10,964 febrile infants identified had RVPCR. Fifty-five percent of these were positive for a respiratory virus; 35 percent for HRV alone. Overall, 9.5 percent had bacterial infection. The likelihood of bacterial infection was increased for febrile infants with HRV detected versus those with non-HRV viruses (7.8 versus 3.7 percent; relative risk, 2.12). No significantly different risk of was seen for HRV-positive infants at any age. No meaningful difference was seen in the risk of invasive (IBI) for infants aged 1 to 28 days; the likelihood of IBI was reduced for infants aged 29 to 90 days with HRV (relative risk, 0.52).

"HRV detection may be relevant in considering risk of IBI for 29 to 90 days of age," the authors write.

Two authors disclosed financial ties to BioFire Diagnostics.

Explore further: Herpes simplex infrequently found in infant meningitis eval

More information: Abstract/Full Text (subscription or payment may be required)

Related Stories

Herpes simplex infrequently found in infant meningitis eval

January 4, 2018
(HealthDay)—Young infants assessed for central nervous system (CNS) infection rarely have herpes simplex virus (HSV), according to a study published online Jan. 3 in Pediatrics.

Step-by-step approach valid for febrile infants

July 6, 2016
(HealthDay)—The Step-by-Step approach is valid for identifying febrile infants at risk for invasive bacterial infection (IBI), according to a study published online July 5 in Pediatrics.

No reduced risk of T1DM with hydrolyzed casein infant formula

January 4, 2018
(HealthDay)—Weaning to an extensively hydrolyzed casein formula is not associated with reduced incidence of type 1 diabetes among at-risk infants, according to a study published in the Jan. 2 issue of the Journal of the ...

'Modest at best' discriminatory ability for CBC test in infants

September 12, 2017
(HealthDay)—Complete blood cell count parameters at commonly used or optimal thresholds do not offer high accuracy in identifying invasive bacterial infections (IBIs) in febrile infants (≤60 days of age), according to ...

Drop in proportion of neonates with long IV therapy for UTI

November 4, 2017
(HealthDay)—From 2005 to 2015 there was a decrease in the proportion of infants aged ≤60 days with a urinary tract infection (UTI) who received four or more days of intravenous (IV) antibiotics, according to a study published ...

Clinical practice guideline on UTI in febrile young reaffirmed

November 29, 2016
(HealthDay)—The 2011 clinical practice guideline (CPG) on urinary tract infection (UTI) in young children has been reaffirmed, according to a report published online Nov. 28 in Pediatrics.

Recommended for you

The effects of happiness and sadness on children's snack consumption

February 19, 2018
A University of Texas at Dallas psychologist has examined the preconceptions about the effects of emotions on children's eating habits, creating the framework for future studies of how dietary patterns evolve in early childhood.

Cycle of infant reflux signals a call to help mothers

February 14, 2018
Western Sydney University research has found that first-time mothers with mental health issues – in particular, maternal anxiety – are five times as likely to have their baby noted as having reflux when admitted to hospital.

Safe-sleep recommendations for infants have not reduced sudden deaths in newborns

February 14, 2018
An analysis of trends in sudden unexpected infant death (SUID) over the past two decades finds that the drop in such deaths that took place following release of the 1992 American Academy of Pediatrics (AAP) "back to sleep" ...

Most children with sickle cell anemia not receiving key medication to stay healthy

February 13, 2018
One of the greatest health threats to children with sickle cell anemia is getting a dangerous bacterial infection—but most are not receiving a key medication to reduce the risk, a new study suggests.

Premature babies' low blood pressure puzzle explained

February 13, 2018
Scientists have discovered crucial new information about how a foetus develops which could explain why very premature babies suffer low blood pressure and other health problems.

Babies face higher SIDS risk in certain states

February 12, 2018
(HealthDay)—Sudden infant death syndrome (SIDS) claims the lives of some 3,500 babies in the United States each year, but its toll is far heavier in some states than others, health officials report.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.