Majority of late preterm infants suffer from morbidities resulting in hospital stay

May 5, 2018, Pediatric Academic Societies

A new study found the majority of late preterm infants (LPTs) suffer from morbidities resulting in hospital stay. Although factors that result in LPT births do contribute to morbidity, physiological immaturity plays an important role in producing poorer outcomes. The research will be presented during the Pediatric Academic Societies (PAS) 2018 Meeting in Toronto.

LPTs constitute 70 percent of the preterm population. Common neonatal morbidities are higher in this group compared to term infants. Although this increased risk is attributed to physiological immaturity, recent studies indicate that immaturity itself may not be the sole cause of morbidity as all premature infants experience this risk, but suffer different outcomes. Some studies demonstrate that the risk of morbidities is determined by the causes of with immaturity acting as modulator. The relative contribution of these factors is unclear. The objective of this study was to assess the role of indications of in LPT in determination of common neonatal morbidities that result in .

The study was conducted as a of LPTs born in a single tertiary care centre between April 2014 and February 2016. Researchers categorized indications of birth as threatened (TPTL), preterm premature rupture of membrane (PPROM) and medically indicated deliveries, which included maternal and fetal pathologies. Risk of hypoglycemia, hyperbilirubinemia, use of CPAP, and apnea of prematurity in LPT were estimated by calculating unadjusted and adjusted for risk ratios using multiple regression analysis with PPROM as a reference category.

PPROM was responsible for 38.4 percent of deliveries, TPTL in 22.8 percent, and 39.1 percent were delivered due to various obstetric and fetal indications with pre-eclampsia and intrauterine growth restriction being the most common reason for medically indicated preterm deliveries. All morbidities were significant across gestational age, with increased risk with decreased gestational age, except hypoglycemia where the incident was highest at 36 weeks (66.7 percent), versus 28.5 percent at 35 weeks, and 22.7 percent at 34 weeks (p value=0.039).

Dr. Melissa Lorenzo will present the abstract, "Morbidity Risk Among Late Term Preterm Infants: Immaturity vs Indication of Delivery," during the PAS 2018 Meeting on Tuesday, May 8 at 7:30 a.m. EDT.

Explore further: Study looks at the impact of fetal gender on the risk of preterm birth

Related Stories

Study looks at the impact of fetal gender on the risk of preterm birth

February 2, 2015
In a study to be presented on Feb. 7 in an oral concurrent session at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the impact of fetal gender on ...

Study shows heightened risks for premature babies in Bangladesh

March 21, 2018
A recently published study in Bangladesh titled Clinical outcome of the late preterm infants shows that premature babies can develop major neonatal complications that need admission in a neonatal intensive care unit.

Delayed cord clamping not beneficial for preterm infants

October 31, 2017
(HealthDay)—Delayed cord clamping does not result in lower incidence of death or major morbidity in preterm infants, according to a study published online Oct. 29 in the New England Journal of Medicine to coincide with ...

Vaginal delivery as safe as cesarean for most early preterm births

August 6, 2012
Vaginal delivery for early preterm fetuses presenting head first, or vertex presentation, had a high rate of success with no difference in neonatal mortality compared to cesarean delivery, a new study published in the American ...

Maternal age over 40 is associated with an increased risk of preterm birth

January 31, 2018
Pregnant mothers aged 40 and over may have an increased risk for preterm birth, regardless of confounding factors, according to a study published January 31, 2018 in the open-access journal PLOS ONE by Florent Fuchs from ...

Late premature birth increases risk of recurrent hospitalization for respiratory illness

June 21, 2017
A new study of children up to 2 years of age showed that those born late preterm (34-36 weeks) had a significantly greater risk of recurrent hospitalization due to respiratory illness compared to those who were born full ...

Recommended for you

App helps hearing-impaired parents know when and why their baby is crying

May 23, 2018
For parents Delbert and Sanaz Whetter a crying baby is a particularly difficult challenge. The Whetters are deaf, so when they're in another room they rely on cameras and remote noise-monitors to help keep an eye on their ...

Vendors say pot eases morning sickness. Will baby pay a price?

May 22, 2018
(HealthDay)—Nearly 70 percent of Colorado marijuana dispensaries recommended pot products to manage early pregnancy-related morning sickness, new research reveals.

Pregnancy drug DES might have triggered ADHD in the grandchildren of women who used it

May 21, 2018
A study conducted by researchers at Columbia University's Mailman School of Public Health and Harvard T.H. Chan School of Public Health reported elevated odds for attention deficit hyperactivity disorder (ADHD) in the grandchildren ...

Age-related racial disparity in suicide rates among US youth

May 21, 2018
New research suggests the suicide rate is roughly two times higher for black children ages 5-12 compared with white children of the same age group. The study, funded by the National Institute of Mental Health (NIMH), appears ...

One in 10 parents say their child has gotten sick from spoiled or contaminated food

May 21, 2018
No parent wants to come home from a picnic or restaurant with a little one whose stomachache turns into much worse.

Male depression may lower pregnancy chances among infertile couples, study suggests

May 17, 2018
Among couples being treated for infertility, depression in the male partner was linked to lower pregnancy chances, while depression in the female partner was not found to influence the rate of live birth, according to a study ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.