Majority of late preterm infants suffer from morbidities resulting in hospital stay

May 5, 2018, Pediatric Academic Societies

A new study found the majority of late preterm infants (LPTs) suffer from morbidities resulting in hospital stay. Although factors that result in LPT births do contribute to morbidity, physiological immaturity plays an important role in producing poorer outcomes. The research will be presented during the Pediatric Academic Societies (PAS) 2018 Meeting in Toronto.

LPTs constitute 70 percent of the preterm population. Common neonatal morbidities are higher in this group compared to term infants. Although this increased risk is attributed to physiological immaturity, recent studies indicate that immaturity itself may not be the sole cause of morbidity as all premature infants experience this risk, but suffer different outcomes. Some studies demonstrate that the risk of morbidities is determined by the causes of with immaturity acting as modulator. The relative contribution of these factors is unclear. The objective of this study was to assess the role of indications of in LPT in determination of common neonatal morbidities that result in .

The study was conducted as a of LPTs born in a single tertiary care centre between April 2014 and February 2016. Researchers categorized indications of birth as threatened (TPTL), preterm premature rupture of membrane (PPROM) and medically indicated deliveries, which included maternal and fetal pathologies. Risk of hypoglycemia, hyperbilirubinemia, use of CPAP, and apnea of prematurity in LPT were estimated by calculating unadjusted and adjusted for risk ratios using multiple regression analysis with PPROM as a reference category.

PPROM was responsible for 38.4 percent of deliveries, TPTL in 22.8 percent, and 39.1 percent were delivered due to various obstetric and fetal indications with pre-eclampsia and intrauterine growth restriction being the most common reason for medically indicated preterm deliveries. All morbidities were significant across gestational age, with increased risk with decreased gestational age, except hypoglycemia where the incident was highest at 36 weeks (66.7 percent), versus 28.5 percent at 35 weeks, and 22.7 percent at 34 weeks (p value=0.039).

Dr. Melissa Lorenzo will present the abstract, "Morbidity Risk Among Late Term Preterm Infants: Immaturity vs Indication of Delivery," during the PAS 2018 Meeting on Tuesday, May 8 at 7:30 a.m. EDT.

Explore further: Study looks at the impact of fetal gender on the risk of preterm birth

Related Stories

Study looks at the impact of fetal gender on the risk of preterm birth

February 2, 2015
In a study to be presented on Feb. 7 in an oral concurrent session at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the impact of fetal gender on ...

Study shows heightened risks for premature babies in Bangladesh

March 21, 2018
A recently published study in Bangladesh titled Clinical outcome of the late preterm infants shows that premature babies can develop major neonatal complications that need admission in a neonatal intensive care unit.

Delayed cord clamping not beneficial for preterm infants

October 31, 2017
(HealthDay)—Delayed cord clamping does not result in lower incidence of death or major morbidity in preterm infants, according to a study published online Oct. 29 in the New England Journal of Medicine to coincide with ...

Vaginal delivery as safe as cesarean for most early preterm births

August 6, 2012
Vaginal delivery for early preterm fetuses presenting head first, or vertex presentation, had a high rate of success with no difference in neonatal mortality compared to cesarean delivery, a new study published in the American ...

Maternal age over 40 is associated with an increased risk of preterm birth

January 31, 2018
Pregnant mothers aged 40 and over may have an increased risk for preterm birth, regardless of confounding factors, according to a study published January 31, 2018 in the open-access journal PLOS ONE by Florent Fuchs from ...

Late premature birth increases risk of recurrent hospitalization for respiratory illness

June 21, 2017
A new study of children up to 2 years of age showed that those born late preterm (34-36 weeks) had a significantly greater risk of recurrent hospitalization due to respiratory illness compared to those who were born full ...

Recommended for you

Teen tattoos: Half of parents concerned about negative health effects, impact on employment

August 20, 2018
Seventy-eight percent of parents in a national poll had a clear answer when asked how they would react if their own teen wanted a tattoo: absolutely not.

First biomarker evidence of DDT-autism link

August 16, 2018
A study of more than 1 million pregnancies in Finland reports that elevated levels of a metabolite of the banned insecticide DDT in the blood of pregnant women are linked to increased risk for autism in the offspring. An ...

Blood test may identify gestational diabetes risk in first trimester

August 16, 2018
A blood test conducted as early as the 10th week of pregnancy may help identify women at risk for gestational diabetes, a pregnancy-related condition that poses potentially serious health risks for mothers and infants, according ...

Artificial placenta created in the laboratory

August 14, 2018
In order to better understand important biological membranes, it is necessary to explore new methods. Researchers at Vienna University of Technology (Vienna) have succeeded in creating an artificial placental barrier on a ...

The inequalities of prenatal stress

August 14, 2018
Exposure to an acute stress in utero can have long-term consequences extending into childhood – but only among children in poor households, according to a new Stanford study that looked at the long-term impact of acute, ...

Promoting HPV vaccine doesn't prompt risky sex by teens: study

August 13, 2018
(HealthDay)—Controversial state laws that promote vaccinating kids against the human papillomavirus (HPV) do not increase the likelihood that teens will engage in risky sexual behavior, a new study contends.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.