FDA approves new pill to reduce pain from endometriosis

July 24, 2018 by Linda A. Johnson
FDA approves new pill to reduce pain from endometriosis
This undated image provided by AbbVie in July 2018 shows packaging for the company's drug Orilissa (elagolix). On Tuesday, July 24, 2018, the company said that The Food and Drug Administration approved its the drug for pain during menstruation and at other times. (AbbVie via AP)

A new treatment for pain caused by endometriosis was approved Tuesday by U.S. regulators.

The common condition involves abnormal tissue growth from the uterus that can cause and infertility.

Drugmaker Abbvie said the Food and Drug Administration approved the drug, Orilissa, for pain during menstruation and intercourse and at other times. Abbvie says it's the first new pill for endometriosis in a decade.

In testing, it significantly reduced in about 45 percent of women given a low dose and 75 percent given a high dose, compared to about 20 percent of women given dummy pills. Reduction of pain outside menstruation was slightly lower.

The drug works by reducing production of the . That caused side effects in some participants, including hot flashes, headaches and bone thinning.

Orilissa will cost $845 every four weeks, without insurance.

An estimated 1 in 10 women of reproductive age has endometriosis. Treatment usually begins with over-the-counter pain relievers, opioid painkillers and . Other options include injections of hormone-suppressing drugs, which have significant side effects, and surgery.

The new pill provides more flexible dosing in lowering estrogen levels, according to Dr. Hugh Taylor of Yale-New Haven Hospital. A consultant to AbbVie, he helped lead key studies of Orilissa.

Explore further: Are you ignoring endometriosis?

Related Stories

Are you ignoring endometriosis?

May 25, 2018
(HealthDay)—Endometriosis is a painful condition affecting many women, yet often years pass before it's diagnosed.

Lower-, higher-dose elagolix beneficial for endometriosis

May 22, 2017
(HealthDay)—Lower- and higher-dose elagolix are beneficial for women with endometriosis, according to research published online May 19 in the New England Journal of Medicine to coincide with the 13th World Congress on Endometriosis, ...

Pregnancy doesn't 'cure' endometriosis, so where does this advice come from?

December 18, 2017
Many Australian women with endometriosis are reporting they're being advised a reliable treatment or even possible cure for their endometriosis is to "go away and have a baby". This message is consistent with what women from ...

It's OK to skip your period while on the pill

May 17, 2018
The pill is the most common form of contraception in Australia, with up to 60% of young women choosing this option to prevent pregnancy.

Study tests potential new drug to reduce pain and symptoms of endometriosis

October 9, 2012
(Medical Xpress)—According to the Centers for Disease Control (CDC), endometriosis, a gynecological disorder in which cells from the uterus lining grow in other areas of the body, is the number one reason for a hysterectomy ...

Low-dose 'pill' linked to pain during orgasm, study finds

May 3, 2013
(HealthDay)—Women taking birth control pills with lower amounts of estrogen—a commonly prescribed contraceptive—may be at higher risk for chronic pelvic pain and pain during orgasm, according to new research.

Recommended for you

Why mothers in mainland China, Hong Kong and Taiwan choose cesarean delivery

October 16, 2018
Pregnant women in mainland China, Hong Kong, and Taiwan are more likely to express preference for cesarean section (CS) as their mode of delivery later in pregnancy and postpartum, as compared to early in pregnancy, according ...

Importance of cell cycle and cellular senescence in the placenta discovered

October 15, 2018
Working with researchers from Stanford University and St. Anna Children's Cancer Research, researchers from Jürgen Pollheimer's laboratory at the Medical University of Vienna's Department of Obstetrics and Gynecology have ...

C-section rates have nearly doubled since 2000: study

October 12, 2018
(HealthDay)—The number of women delivering babies via cesarean section has nearly doubled worldwide since 2000, to about 21 percent, new research shows.

Study of nearly 41,000 women who almost died giving birth shows who's most at risk

October 10, 2018
Tens of thousands of American women each year need emergency treatment to save their lives while they deliver their babies, or immediately after. A new study shows how much their risk of a life-threatening birth depends on ...

In childbirth, when to begin pushing does not affect C-section rates

October 9, 2018
More than 3 million women in the United States give birth each year. But obstetricians have differing opinions about when women should begin pushing during labor and whether the timing of pushing increases the likelihood ...

Why single embryo transfer during IVF sometimes results in twins or triplets

October 8, 2018
It has been known for some time that it is better to transfer a single embryo to a woman's womb during assisted reproduction treatment (ART) rather than several embryos in order to avoid a multiple pregnancy and the risks ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.