New treatment option available for men suffering from benign prostatic hyperplasia

July 9, 2018, University of California - San Diego
New treatment option available for men suffering from benign prostatic hyperplasia
Andrew Picel, M.D., interventional radiologist at UC San Diego Health. Credit: UC San Diego Health

Physicians at UC San Diego Health are now offering prostate artery embolization (PAE) as a new treatment option for men with benign prostatic hyperplasia (BPH), or an enlarged prostate. The minimally invasive procedure is an alternative to surgery, with no hospital stay, little operative pain and lower cost.

"PAE has been available in Europe as a option for an for several years," said Andrew Picel, MD, interventional radiologist at UC San Diego Health. "With the recent FDA approval of this procedure, we are happy to offer this as an alternative to surgery for patients who are good candidates."

Using X-ray guidance, interventional radiologists insert a small catheter into an artery in the upper thigh or wrist. The catheter is then threaded into the arteries supplying the . Small particles are injected to partially block the blood flow to the prostate. This reduces the size of the prostate and relieves symptoms of BPH.

Picel and team have treated almost 20 patients with the new procedure.

"We have seen excellent results with the patients we have treated so far," said Alexander Norbash, chair of Radiology at UC San Diego School of Medicine. "The benefits of PAE allow patients to recover at home and return more quickly to normal activities. Symptoms may start to improve as early as the first week after treatment."

Several surgery options are also available, including transurethral resection of the prostate (TURP), which is considered the gold standard for treatment of BPH. However, TURP requires full anesthesia, an overnight , three to six weeks of recovery time and is associated with sexual side effects.

Enlarged prostates affect at least half of men over 60 years of age. Symptoms include a frequent urge to urinate, especially at night; leakage or dribbling of urine; a weak urine stream and trouble beginning urination. BPH can cause other problems if untreated, such as kidney, bladder and urinary tract infections.

UC San Diego Health interventional radiologists and urologists screen patients as potential candidates for PAE. Typically, candidates are 50 to 85 years of age, have symptoms, have unsuccessfully tried medications within the last six months and have undergone assessment for . It is important that patients understand the full range of available treatment options to make an informed decision and pursue the treatment best for their individual medical situation.

"It is great that patients now have a minimally invasive alternative to surgery to help with this common health problem," said Picel. "The collaboration between interventional radiology and urology is why we are seeing such success treating with PAE."

Explore further: Nonsurgical treatment for enlarged prostate remains effective for years

More information: In March of 2017, UC San Diego Health launched a clinical trial on PAE, making it one of the first medical centers in California to offer PAE. The clinical trial at UC San Diego Health is still ongoing and available to men who meet criteria clinicaltrials.ucbraid.org/trial/NCT03055624

Related Stories

Nonsurgical treatment for enlarged prostate remains effective for years

March 8, 2017
A minimally invasive treatment that reduces urinary tract symptoms for men with enlarged prostates maintains its effectiveness for at least three years after patients undergo the therapy, according to research being presented ...

Studying a new treatment for a common men's condition

August 17, 2017
A New Zealand-first research study happening in Canterbury could make treatment of a common male condition easier and less painful.

Nonsurgical treatment turns back the clock, shrinks enlarged prostate

April 15, 2013
Men with a common condition that causes frequent nighttime trips to the bathroom can get relief with a minimally invasive treatment that shrinks the prostate, suggests a study being presented at the Society of Interventional ...

Prostate treatment lasts, preserves fertility

March 24, 2014
Shrinking the prostate without surgery can provide long-term relief to men with this common condition that causes annoying symptoms, such as frequent trips to the bathroom, suggests a study of nearly 500 men. According to ...

Interventional radiology offers new treatment for enlarged prostates

March 2, 2015
Men with benign prostatic hyperplasia (BPH), a condition in which the prostate is enlarged but not cancerous, have a new, breakthrough treatment option that is less invasive and has fewer complications than other minimally ...

Recommended for you

Antifungal agent found to be possible treatment for porphyria

September 24, 2018
A large team of researchers from Spain, France and the U.S. has found that a common antifungal agent might be useful as a treatment for a rare type of porphyria. In their paper published in the journal Science Translational ...

New findings on the muscle disease Laing early-onset distal myopathy

September 24, 2018
New avenues are now being opened toward treatment of Laing distal myopathy, a rare disorder that causes atrophy of the muscles in the feet, hands and elsewhere. In a study published in the journal PNAS, researchers have identified ...

Insulin shows great potential against chronic colitis

September 24, 2018
Diabetes is not the only disease on which insulin has an effect, it appears. In a new study using tests on mice, researchers from the University of Copenhagen, among others, have discovered a new method for treating chronic ...

A new approach to developing a vaccine against vivax malaria

September 21, 2018
A novel study reports an innovative approach for developing a vaccine against Plasmodium vivax, the most prevalent human malaria parasite outside sub-Saharan Africa. The study led by Hernando A. del Portillo and Carmen Fernandez-Becerra, ...

Pre-clinical success for a universal flu vaccine offers hope for third generation approach

September 21, 2018
Researchers from the University of Oxford's Department of Zoology have demonstrated pre-clinical success for a universal flu vaccine in a new paper published in Nature Communications.

Researchers define possible molecular pathway for neurodegeneration in prion diseases

September 21, 2018
A new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.