Trigeminal nerve stimulation beats sham tx for peds ADHD

Trigeminal nerve stimulation beats sham tx for peds ADHD

(HealthDay)—Trigeminal nerve stimulation (TNS) showed efficacy when compared with a similar sham procedure for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children, according to a double-blind, controlled pilot study published in the April issue of the Journal of the American Academy of Child & Adolescent Psychiatry.

James J. McGough, M.D., from the University of California in Los Angeles, and colleagues randomly assigned 62 children (aged 8 to 12 years with full-scale IQ of ≥85) diagnosed with ADHD to four weeks of nightly treatment with either active or sham TNS followed by one week without intervention. Study assessments included weekly clinician-administered ADHD Rating Scales (ADHD-RS) and Clinical Global Impression (CGI) scales plus quantitative electroencephalography at baseline and week 4.

The researchers found that ADHD-RS total scores showed significant group-by-time interactions. Active treatment was also associated with CGI-Improvement (number needed to treat was three). There was increased spectral power in the right frontal and frontal midline frequency bands with active TNS, as seen on resting-state quantitative electroencephalography. No clinically meaningful adverse events were reported in either group.

"Additional research should examine treatment response durability and potential impact on with sustained use," the authors write.

Several authors disclosed financial ties to NeuroSigma, which provided the study devices.


Explore further

First double-blind controlled trial of TNS shows reduced symptoms in some children with ADHD with minimal risk

More information: Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Copyright © 2019 HealthDay. All rights reserved.

Citation: Trigeminal nerve stimulation beats sham tx for peds ADHD (2019, April 16) retrieved 27 May 2019 from https://medicalxpress.com/news/2019-04-trigeminal-nerve-sham-tx-peds.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
1 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more