Apathy: The forgotten symptom of dementia

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Apathy is the most common neuropsychiatric symptom of dementia, with a bigger impact on function than memory loss—yet it is under-researched and often forgotten in care.

A new study has found that is present nearly half of all people with , with researchers finding it is often distinct from depression.

Although common, apathy is often ignored as it is less disruptive in settings such as than symptoms like aggression. Defined by a loss of interest and emotions, it is extremely distressing for families and it is linked with more severe dementia and worse clinical symptoms.

Now, research led by the University of Exeter and presented at the Alzheimer's Association International Conference in LA has analyzed 4,320 people with Alzheimer's disease from 20 cohort studies, to look at the prevalence of apathy over time.

At the start of the study, 45 percent presented with apathy, and 20 percent had persistent apathy over time. Researchers found that a proportion had apathy without depression, which suggests that the symptom might have its own unique clinical and biological profile when compared to apathy with depression and only.

Dr. Miguel de Silva Vasconcelos, of the University of Exeter and King's College London, said : "Apathy is an under-researched and often ignored symptom of dementia. It can be overlooked because people with apathy seem less disruptive and less engaging, but it has a huge impact on the quality of life of people living with dementia, and their families. Where people withdraw from activities, it can accelerate and we know that there are higher mortality rates in people with apathy. It's now time this symptom was recognized and prioritized in research and understanding."

Professor Clive Ballard, of the University of Exeter Medical School, said: "Apathy is the forgotten symptom of dementia, yet it can have devastating consequences. Our research shows just how common apathy is in people with dementia, and we now need to understand it better so we can find effective new treatments. Our WHELD study to improve care home staff training through personalized care and included an exercise programme that improved apathy, so we know we can make a difference. This is a real opportunity for interventions that could significantly benefit thousands of people with dementia. "

The poster is titled "The Course of Apathy in People with Dementia."


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Citation: Apathy: The forgotten symptom of dementia (2019, July 16) retrieved 24 August 2019 from https://medicalxpress.com/news/2019-07-apathy-forgotten-symptom-dementia.html
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