Lymphoma survivors at risk for developing chronic kidney disease

Lymphoma survivors at risk for developing chronic kidney disease

(HealthDay)—Lymphoma survivors are at substantial long-term risk for chronic kidney disease (CKD) development, according to a study published online July 11 in Leukemia & Lymphoma.

Sanjal H. Desai, M.D., from the Medstar Washington Hospital Center in Washington, D.C., and colleagues describe patterns of long-term CKD in lymphoma survivors. At diagnosis and years 1, 2, 5, and 10, (GFR) was recorded.

The researchers found that among 397 patients (median age, 55.3 years; 54 percent male; 60 percent African-American), 42 percent had hypertension, 15 percent had , 13 percent had hyperuricemia, 86 percent received chemotherapy, and 14 percent had baseline CKD. Just under one-third of patients (31 percent) developed CKD within 10 years of lymphoma diagnosis. There was a significant increase noted in the probability of CKD development with time (23 percent at year 1 increased to 41 percent at year 10). The investigators observed a decline in GFR of 4.6 mL/min/per year. CKD was predicted by age, hypertension, hyperuricemia, and diabetes (in ).

"These findings underscore the need to monitor renal function in long-term lymphoma survivors and lay foundation for future prospective studies to define strategies to prevent CKD in lymphoma survivors," the authors write.


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Citation: Lymphoma survivors at risk for developing chronic kidney disease (2020, July 20) retrieved 12 August 2020 from https://medicalxpress.com/news/2020-07-lymphoma-survivors-chronic-kidney-disease.html
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