Gluten intake not tied to cognition in women without celiac disease

Gluten intake not tied to cognition in women without celiac disease

Long-term gluten intake is not associated with cognitive scores in middle-aged women without celiac disease, according to a study published online in JAMA Network Open.

Yiqing Wang, Ph.D., from Massachusetts General Hospital in Boston, and colleagues examined whether gluten intake is associated with cognitive function in women without . The analysis included 13,494 women participating in the Nurses' Health Study II with dietary assessments from 1991 to 2015 and cognitive assessments from 2014 to 2019.

The researchers found that after controlling for demographic and , there were no significant differences in standardized cognitive scores by quintile of gluten intake when comparing the highest and lowest quintiles (psychomotor speed and attention: P for trend = 0.22; learning and working memory: P for trend = 0.30; global cognition: P for trend = 0.78). Even when further adjusting for major sources of dietary gluten (e.g., refined grains or whole grains), comparing decile categories of gluten intake, using gluten intake updated at each previous questionnaire cycle, or modeling changes in gluten intake, the null associations persisted.

"Our results do not support recommendations to restrict dietary gluten to maintain cognitive function in the absence of celiac disease or established ," conclude the authors.

Several authors reported financial ties to the pharmaceutical and publishing industries.


Explore further

Consumer health: Summer eating with celiac disease

More information: Abstract/Full Text
Journal information: JAMA Network Open

Copyright © 2021 HealthDay. All rights reserved.

Citation: Gluten intake not tied to cognition in women without celiac disease (2021, June 7) retrieved 26 July 2021 from https://medicalxpress.com/news/2021-06-gluten-intake-tied-cognition-women.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
 shares

Feedback to editors

User comments