Study links metabolic syndrome to poor health outcomes in adults with kidney disease

Study links metabolic syndrome to poor health outcomes in adults with kidney disease
JIM Graphical Abstract. Credit: JIM Graphical Abstract

A study published in the Journal of Internal Medicine has uncovered a high prevalence of metabolic syndrome in adults with moderate chronic kidney disease, and found that metabolic syndrome increases their risk of premature death and cardiovascular problems.

Among 5,110 adults in Germany who had chronic kidney disease, 64.3% also had metabolic syndrome. During 6.5 years of follow-up, 605 patients died and 650 experienced major cardiovascular events (such as heart attacks and strokes). Patients with metabolic syndrome had a 26% higher risk of dying and a 48% higher risk of experiencing cardiovascular events. The risk increased steadily with a growing number of metabolic syndrome components, such as increased , blood sugar levels, triglycerides, and blood pressure, and decreased HDL cholesterol.

"Although our study uncovered a shockingly high frequency of metabolic syndrome in this high-risk patient group, there's a motivating message for our patients: each component avoided might considerably decrease the risk for a cardiovascular endpoint or premature death," said senior author Florian Kronenberg, MD, of the Medical University of Innsbruck, in Austria.

More information: Lorenz M. Pammer et al, Association of the metabolic syndrome with mortality and major adverse cardiac events: A large chronic kidney disease cohort, Journal of Internal Medicine (2021). DOI: 10.1111/joim.13355

Journal information: Journal of Internal Medicine
Provided by Wiley
Citation: Study links metabolic syndrome to poor health outcomes in adults with kidney disease (2021, August 4) retrieved 29 March 2024 from https://medicalxpress.com/news/2021-08-links-metabolic-syndrome-poor-health.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Metabolic syndrome linked to increased risk of second stroke, death

2 shares

Feedback to editors