This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:


trusted source


First-of-its-kind study confirms safety of distal radial artery access for cardiac catheterization

hand grip
Credit: Unsplash/CC0 Public Domain

One-year findings from the Distal versus Proximal Radial Artery Access for Cardiac Catheterization and Intervention (DIPRA) study were presented as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2023 Scientific Sessions. The single-center, randomized-controlled trial evaluated outcomes of hand function and effectiveness of conventional proximal radial artery (PRA) access compared to distal radial artery (DRA) access for cardiac catheterization.

Current guidelines for patients undergoing percutaneous intervention recommend PRA access. A complication of PRA is radial artery occlusion, or a blocking of the vessel, which can compromise the access of the artery for future coronary bypass surgery, dialysis or other cardiovascular procedures.

The DIPRA study randomized 300 patients 1:1 to through either DRA or PRA. The primary endpoint was change in from baseline to one year. Hand function was a composite of the QuickDASH questionnaire, hand grip test, and thumb-forefinger pinch test. Secondary endpoints included access feasibility, radial artery patency, and complications.

Of 216 patients who completed one-year follow-up, 112 were randomized to DRA and 104 to PRA. Both groups had similar access site bleeding rates (DRA 0% vs. PRA 1.4%; p=0.25). Six DRA patients failed access compared to 2 PRA patients. Radial artery occlusion occurred in 1 PRA patient vs. 2 in DRA. At 1 year, there was no significant difference in the change of hand function, in hand grip (DRA 0.7 [-3, 4.5] vs. PRA 1.3 [-2, 4.3] kg; P=0.57), pinch grip (DRA -0.1 [-1.1, 1] vs. PRA -0.3 [-1, 0.7] kg; P=0.66), and QuickDASH (DRA 0 [-6.6, 2.3] vs. PRA 0 [-4.6, 2.9] points, P= 0.58). The composite of hand function was comparable between PRA and DRA at one year.

"We know that radial artery occlusion is a potential complication of repeated heart catheterizations through the wrist. We also know that distal radial artery access in the base of the thumb carries a lower risk for this complication," said Karim Al-Azizi, MD, FSCAI, Interventional Cardiologist at Baylor Scott & White Health in Plano, Texas and lead author of the study. "The one-year safety results presented at SCAI are reassuring and offer physicians an alternative approach for patients who need radial access, such as patients with for dialysis access or coronary artery disease patients who need bypass grafting."

Citation: First-of-its-kind study confirms safety of distal radial artery access for cardiac catheterization (2023, May 18) retrieved 21 September 2023 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Novel distal radial access for cardiac catheterization shown as a safe strategy compared to conventional radial access


Feedback to editors