This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:

fact-checked

peer-reviewed publication

reputable news agency

proofread

High BMI in adolescence linked to early chronic kidney disease in young adulthood

High BMI in adolescence linked to early CKD in young adulthood

High body mass index (BMI) in late adolescence is associated with early chronic kidney disease (CKD) in young adulthood, according to a study published online Dec. 11 in JAMA Pediatrics.

Avishai M. Tsur, M.D., from the Israel Defense Forces, Medical Corps, in Ramat Gan, and colleagues examined the association between BMI and early CKD in young adulthood (younger than 45 years).

The analysis included 629,168 adolescents (54.5 and 45.5 percent males and females, respectively) aged 16 to 20 years, medically evaluated for mandatory military service. Early CKD was defined as stage 1 to 2 CKD based on moderately or severely increased albuminuria, with an estimated glomerular filtration rate of ≥60 mL/min/1.73 m2.

The researchers found that during a mean follow-up of 13.4 years for males and females, 0.3 percent developed early CKD. The adjusted hazard ratios for CKD were 1.8, 4.0, 6.7, and 9.4 for adolescents with high-normal BMI, overweight, mild obesity, and severe obesity, respectively, among males.

The corresponding hazard ratios among females were 1.4, 2.3, 2.7, and 4.3. When the was limited to individuals who were seemingly healthy as adolescents, those surveyed up to 30 years of age, or those free of diabetes and hypertension at the end of follow-up, the results were similar.

"Given the increasing rates among , our findings are a harbinger of the potentially preventable increasing burden of CKD and subsequent cardiovascular disease," the authors write.

More information: Avishai M. Tsur et al, Adolescent Body Mass Index and Early Chronic Kidney Disease in Young Adulthood, JAMA Pediatrics (2023). DOI: 10.1001/jamapediatrics.2023.5420

Journal information: JAMA Pediatrics

Copyright © 2023 HealthDay. All rights reserved.

Citation: High BMI in adolescence linked to early chronic kidney disease in young adulthood (2023, December 12) retrieved 19 April 2024 from https://medicalxpress.com/news/2023-12-high-bmi-adolescence-linked-early.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Arterial stiffness may cause metabolic syndrome in adolescents via an increase in fasting insulin and LDL cholesterol

3 shares

Feedback to editors