This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:

fact-checked

trusted source

proofread

Research suggests probiotics plus vitamin D supplements may benefit people with schizophrenia

vitamin D
Credit: CC0 Public Domain

Previous studies have questioned whether gut microbe imbalances and vitamin D deficiency may be linked to schizophrenia.

New research published in Neuropsychopharmacology Reports now indicates that taking probiotics plus vitamin D supplements may improve cognitive function in individuals with the disease.

For the study, 70 adults with schizophrenia were randomized to take a placebo or probiotic supplements plus 400 IU vitamin D daily for 12 weeks. Severity of the disease and cognitive function were evaluated by tests called the Positive and Negative Syndrome Scale (PANSS) and the 30-point Montreal Cognitive Assessment (MoCA), respectively.

A total of 69 patients completed the study. The MoCA score increased by 1.96 units in the probiotic-containing supplement group compared with the . Also, the percentage of patients with MoCA scores of 26 or higher (indicating normal cognition) rose significantly in the intervention group. Between-group differences in PANSS scores were not significant.

"Probiotics may be a novel way to treat by regulating ," said corresponding author Gita Sadighi, MD, of the University of Social Welfare and Rehabilitation Sciences, in Iran.

More information: Co-administration of probiotic and vitamin D significantly improves cognitive function in schizophrenic patients: A double-blinded Randomized controlled trial, Neuropsychopharmacology Reports (2024). DOI: 10.1002/npr2.12431 , onlinelibrary.wiley.com/doi/10.1002/npr2.12431

Provided by Wiley
Citation: Research suggests probiotics plus vitamin D supplements may benefit people with schizophrenia (2024, April 10) retrieved 15 June 2024 from https://medicalxpress.com/news/2024-04-probiotics-vitamin-d-supplements-benefit.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Sex differences seen in cognitive impairment for tardive dyskinesia in schizophrenia

7 shares

Feedback to editors