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Parkinson's & Movement disorders news

Parkinson's & Movement disorders

What the trained eye cannot see: Detecting movement defects in early stage Parkinson's disease

A technique that uses videos and machine learning to quantify motor symptoms in early-stage Parkinson's disease could help reveal signs of the disease and other movement disorders earlier, which could lead to better treatment ...

Genetics

Researchers discover rare sequence variants that associate with a high risk of Parkinson's disease

Scientists at deCODE genetics, a subsidiary of AMGEN, have discovered rare sequence variants, predicted to cause a loss of function of ITSN1, that are associated with a high risk of Parkinson's disease. The findings also ...

Parkinson's & Movement disorders

Fecal microbiota transplant no aid for Parkinson's disease

Fecal microbiota transplantation (FMT) is safe but does not offer clinically meaningful improvements for Parkinson's disease (PD), according to a study published online July 29 in JAMA Neurology.

Health

What your gait says about your health

Walking requires a huge number of signals between your brain and the muscles in your arms, chest, back, abdomen, pelvis and legs. Something that looks relatively straightforward is in fact incredibly complex. And the pace ...

Neuroscience

Gut protein may protect brain cells in Parkinson's disease

Nearly 10 million people worldwide suffer from Parkinson's disease (PD), a condition causing muscle rigidity and tremors due to the loss of the chemical dopamine in the brain. One cause of PD is exposure to toxins. In a recent ...

Parkinson's & Movement disorders

Machine learning helps define new subtypes of Parkinson's disease

Researchers at Weill Cornell Medicine have used machine learning to define three subtypes of Parkinson's disease based on the pace at which the disease progresses. In addition to having the potential to become an important ...

Parkinson's & Movement disorders

Study: Get moving to put the brakes on early Parkinson's

A new study suggests that people with early-stage Parkinson's disease who regularly got one to two hours of moderate exercise twice a week, like walking or gardening, may have less trouble balancing, walking and doing daily ...

Medical research

Study details lessons learned from remote clinical studies

Traditional, in-person clinical research studies have long been plagued by slow and often unsuccessful recruitment. The limits of site location, which sometimes requires participants to travel long distances, and the reliance ...

Neuroscience

Dementia protein changes discovered in terminal childhood disease

In a world-first, researchers at Newcastle University have found that the brains of infants who sadly passed away with an extremely rare genetic condition, Krabbe disease, have similar changes to those seen in two age-related ...

Medical research

Transforming 'undone science' into 'done science'

Mannitol, a natural sweetener, may help treat Parkinson's disease, yet was not being tested in clinical trials. The story of mannitol is one of many examples of "undone science": research questions unfunded or ignored for ...

Parkinson's & Movement disorders

Parkinson's disease mutation misdirects iron in the brain

A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National ...

Parkinson's & Movement disorders

Protein test could lead to earlier and better diagnosis of Parkinson's

Scientists at the Oxford Parkinson's Disease Centre (OPDC) have been able to use a highly-sensitive method called α-synuclein real-time quaking-induced conversion (αSyn-RT-QuIC) to observe the clumping of alpha-synuclein ...

Parkinson's & Movement disorders

Are scientists homing in on a cure for Parkinson's disease?

A molecule that shows promise in preventing Parkinson's disease has been refined by scientists at the University of Bath in the UK, and has the potential to be developed into a drug to treat the deadly neurodegenerative disease.

Parkinson's & Movement disorders

Study: People with Parkinson's may speak up to 60% less

Parkinson's disease can disrupt multiple aspects of a person's functioning, including the volume, rhythm and intonation of their speech. In some cases, a person with Parkinson's will hesitate to speak or pause when speaking, ...

Neuroscience

Wearable vibration device may ease Parkinson's tremor

Physiotherapist David Putrino was working on a vibrating glove to help deaf people experience live music when a friend mentioned that the same technology might stop tremors in people with Parkinson's disease.