Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice. Published in the journal PLOS Biology, the ...
Feb 18, 2025
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Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle weakness and eventually death. While significant strides have ...
Feb 18, 2025
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In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that damage brain cells. The process of proteins spontaneously clumping is called protein aggregation and ...
Feb 17, 2025
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From a study that analyzed brain images of more than 2,500 people with Parkinson's disease in 20 different countries, scientists have been able to identify patterns of neurodegeneration and create metrics for each of the ...
Feb 12, 2025
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Fingernail-sized vibrating gadgets, similar to the tiny devices that make your cellphone buzz, could help people with Parkinson's disease navigate the world with more confidence and ease. The vibrating devices, which may ...
Feb 12, 2025
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Researchers at Karolinska Institutet have discovered new insights into brain changes in Parkinson's disease using advanced imaging techniques.
Feb 12, 2025
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A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream ...
Feb 11, 2025
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The U.S. Food and Drug Administration has approved Onapgo (apomorphine hydrochloride) injection as the first and only subcutaneous apomorphine infusion device for the treatment of motor fluctuations in patients with advanced ...
Feb 6, 2025
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Lewy body diseases (LBDs) are a class of debilitating neurodegenerative disorders linked to the abnormal aggregation of the protein α-synuclein in nerve cells. When misfolded, this protein can produce clumps known as Lewy ...
The GLP-1 drug, exenatide, has no positive impact on the movement, symptoms or brain imaging of people with Parkinson's, finds a new study led by UCL researchers.
Feb 4, 2025
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