Methotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is the most commonly used drug for systemic rheumatic diseases worldwide and is the first drug ...
Feb 17, 2020
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Novel blood-based biomarkers for dementia could identify disease at an early preclinical stage, serve as surrogate outcomes for clinical trials of investigational therapies and even identify future potential therapeutic targets. ...
Feb 14, 2020
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Chronic kidney disease (CKD) affects 14 percent of adults in the U.S. There are several stages of CKD, but when it progresses to kidney failure, outcomes are quite poor, with those patients dying at a higher rate than patients ...
Feb 13, 2020
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In the largest study of skin cancer rates among gay, lesbian or bisexual individuals, investigators from Brigham and Women's Hospital report important differences in skin cancer prevalence among sexual minorities. Rates of ...
Feb 12, 2020
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Acute kidney injury (AKI) is common and it happens fast. Unlike chronic kidney disease, which often takes years to manifest, patients with AKI experience a rapid deterioration of kidney function over hours or days. Critically ...
Jan 29, 2020
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For most patients, melanoma begins with a small, pigmented spot on their skin that they notice starts to change. Many primary melanomas can be cured by having this lesion removed, but melanoma can also recur and spread; an ...
Jan 20, 2020
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Even as more states begin to legalize marijuana for medicinal and recreational use and more marijuana products become available for consumption, marijuana's cardiovascular effects are not well understood. In a review article ...
Jan 20, 2020
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In 2017, for every victim who died of a firearm injury in the U.S, three individuals survived. But the burden of firearm injuries is not limited to death. A new study led by investigators from Brigham and Women's Hospital ...
Jan 16, 2020
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A new analysis provides evidence that may change the current thinking around categorizing patients with heart failure prior to implanting a left-ventricular assist device (LVAD). Currently, clinicians and regulatory agencies ...
Jan 15, 2020
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Neoadjuvant systemic therapy (NST) can shrink tumors in breast cancer patients and in some cases allow for breast conserving therapy (lumpectomy) who would otherwise require a mastectomy. Yet, in the United States, about ...
Jan 8, 2020
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