Genome-wide association studies (GWAS) have identified thousands of genetic variants that are associated with a wide range of diseases. But these studies often fall short of establishing what a genetic variant does to bring ...
Apr 8, 2021
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Most cancer drugs that target specific genetic mutations are designed for adult cancers rather than those in children, partly because pediatric cancers have fewer mutations. To look for more ways to target childhood cancers, ...
Mar 23, 2021
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A new method for studying gene function shows how high blood sugar and bone density are connected in diabetes patients.
Feb 4, 2021
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By bringing DNA sequencing out of the sequencer and directly to cells, scientists from the McGovern Institute for Brain Research, the Harvard University Department of Stem Cell and Regenerative Biology (HSCRB), and the Broad ...
Jan 6, 2021
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Cancer cell lines, grown from tumor cells and cultivated under laboratory conditions, are a mainstay of cancer research. They provide valuable insights into cancer genomics and biology, but for several reasons, scientists ...
Jan 5, 2021
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The nervous and immune systems have long been thought to be separate entities in the body, but new research has uncovered a direct cellular interaction between the two. Scientists from Harvard Medical School, the Broad Institute ...
Dec 17, 2020
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Cancer mutations often incapacitate critically important genes, forcing tumors to depend heavily on other genes for survival. Such genetic dependencies are attractive targets for new cancer therapies.
Dec 16, 2020
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The vast majority of cancer deaths are attributed to metastasis, or the spread of tumors from one organ to another. Determining if a cancer will metastasize has been all but impossible, but if it does, it becomes more difficult ...
Dec 10, 2020
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When Anna Greka, an institute member at the Broad Institute of MIT and Harvard and a physician at Brigham and Women's Hospital, volunteered to help care for patients with COVID-19 at the peak of Boston's springtime surge, ...
Nov 18, 2020
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Ebola virus is one of the world's deadliest pathogens, and scientists now report new details of how the virus alters the host immune response for its own benefit during infection. In a study published today in Cell, the researchers ...
Nov 9, 2020
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