Researchers investigating a key signaling protein in Huntington's disease describe deleterious effects on heart function, going beyond the disease's devastating neurological impact. By adjusting protein levels affecting an ...
Apr 24, 2018
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Neurobiology researchers have identified a pathway in brain circuitry that, when stimulated, leads to "antidepressive" behavior in animals. If such brain stimulation proves to have similar effects in people, it may eventually ...
Apr 16, 2018
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Experts in pediatric kidney disease have published a new staging system to help doctors better predict the length of time until a child with chronic kidney disease (CKD) will need to undergo a kidney transplant or start receiving ...
Apr 10, 2018
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A systematic study of seven antioxidants commonly taken by or suggested to benefit children and adults affected with mitochondrial disease provides intriguing clues that at least two compounds should be further evaluated ...
Mar 27, 2018
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Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures ...
Mar 22, 2018
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Researchers have discovered a "missing mutation" in severe infant epilepsy—long-suspected genetic changes that might trigger overactive, brain-damaging electrical signaling leading to seizures They also found early indications ...
Mar 20, 2018
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Infants who consumed soy-based formula as newborns had differences in some reproductive-system cells and tissues, compared to those who used cow-milk formula or were breastfed, according to a new study. The researchers say ...
Mar 12, 2018
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Children with mitochondrial diseases who suffered acute metabolic strokes benefited from rapid intravenous treatment with the amino acid arginine, experiencing no side effects from the treatment. The diseases were caused ...
Mar 9, 2018
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Aseem R. Shukla, MD, a pediatric urologist at Children's Hospital of Philadelphia (CHOP), along with several of his colleagues from around the world, have created an innovative program to help address urological needs in ...
Mar 7, 2018
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Researchers studying a rare genetic disorder that causes severe, progressive neurological problems in childhood have discovered insights into biological mechanisms that drive the disease, along with early clues that an amino ...
Feb 22, 2018
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