A new study of influenza infection in an animal model broadens understanding of how the immune system responds to flu virus, showing that the process is more dynamic than usually described, engaging a broader array of biological ...
Sep 28, 2015
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Mitochondria are not only the power plants of our cells, these tiny structures also play a central role in our physiology. Furthermore, by enabling flexible physiological responses to new environments, mitochondria have helped ...
Sep 24, 2015
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Researchers analyzing the complicated genetic influences in inflammatory bowel disease have discovered new gene variants associated with an often-severe type of the disease that affects children under age five. The genes ...
Sep 3, 2015
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Scientists who analyzed the genes involved in 10 autoimmune diseases that begin in childhood have discovered 22 genome-wide signals shared by two or more diseases. These shared gene sites may reveal potential new targets ...
Aug 24, 2015
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Surgeons at The Children's Hospital of Philadelphia (CHOP) joined with colleagues from Penn Medicine recently to complete the world's first bilateral hand transplant on a child. Earlier this month, the surgical team successfully ...
Jul 28, 2015
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Using existing drugs, such as lithium, to restore basic biological processes in human cells and animal models, researchers may have broken a long-standing logjam in devising effective treatments for human mitochondrial diseases.
Jul 20, 2015
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Pediatric researchers have discovered gene locations affecting bone strength in wrist bones, the most common site for fractures in children. Children who have those genetic variants may be at higher-than-average risk of wrist ...
Jun 29, 2015
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Researchers studying the pediatric cancer neuroblastoma have detailed how cancer-driving mutations evolve during chemotherapy, and they hope to exploit this knowledge to design better treatments for children.
Jun 29, 2015
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Short boys are three times more likely than short girls to receive recombinant human growth hormone treatment for idiopathic short stature (ISS), even though in a general pediatric population, equal proportions of both genders ...
Jun 10, 2015
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Cerebral palsy (CP) is the most common cause of childhood disability in the world, affecting between 1 and 2 infants per thousand. But the neurological condition tends to be understudied, especially in developing countries.
May 29, 2015
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