Columbia University School of Engineering and Applied Science

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http://www.engineering.columbia.edu/

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Oncology & Cancer

Designer probiotic treatment for cancer immunotherapy

Researchers at Columbia Engineering have engineered probiotics to safely deliver immunotherapies within tumors. These include nanobodies against two proven therapeutic targets—PD-L1 and CTLA-4. The drugs are continuously ...

Medical research

New test diagnoses Lyme disease within 15 minutes

Some 300,000 people in the U.S. are diagnosed with Lyme disease every year. Caused by Borrelia burgdorferi and transmitted by the bite of infected Ixodes ticks, the disease if left untreated can cause serious neurologic, ...

Oncology & Cancer

Bacteria engineered as Trojan horse for cancer immunotherapy

The emerging field of synthetic biology—designing new biological components and systems—is revolutionizing medicine. Through the genetic programming of living cells, researchers are creating engineered systems that intelligently ...

Neuroscience

Tuning arousal to boost information transmission in the brain

Columbia neural engineers discover a mechanism by which the locus coeruleus modulates information processing in the thalamus; their findings of how sensory information is encoded in the healthy brain may lead to new treatments ...

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