Columbia University School of Engineering and Applied Science

Neuroscience

Discovering how the brain works through computation

Accelerating progress in neuroscience is helping us understand the big picture—how animals behave and which brain areas are involved in bringing about these behaviors—and also the small picture—how molecules, neurons, ...

Oncology & Cancer

Designer probiotic treatment for cancer immunotherapy

Researchers at Columbia Engineering have engineered probiotics to safely deliver immunotherapies within tumors. These include nanobodies against two proven therapeutic targets—PD-L1 and CTLA-4. The drugs are continuously ...

Medical research

New test diagnoses Lyme disease within 15 minutes

Some 300,000 people in the U.S. are diagnosed with Lyme disease every year. Caused by Borrelia burgdorferi and transmitted by the bite of infected Ixodes ticks, the disease if left untreated can cause serious neurologic, ...

Oncology & Cancer

Bacteria engineered as Trojan horse for cancer immunotherapy

The emerging field of synthetic biology—designing new biological components and systems—is revolutionizing medicine. Through the genetic programming of living cells, researchers are creating engineered systems that intelligently ...

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