Dana-Farber Cancer Institute

Oncology & Cancer

New chemical technology boosts potency of targeted cancer therapy

In work that heralds a new, more potent form of targeted therapy for cancer, Dana-Farber Cancer Institute scientists have devised a chemical technology that doesn't just disable malevolent proteins in tumor cells, as current ...

Oncology & Cancer

Researchers identify key source of T cell 'exhaustion'

Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies. All too often, however, they display a frustrating trait inherited ...

Medical research

Study suggests possible way to 'Smac' cancer

In animals, a process of programmed cell death called apoptosis ensures cells die when they should. An opposing force, governed by inhibitor of apoptosis proteins (IAPs), guards against excessive cell death. Together these ...

Immunology

Mechanism for resistance to immunotherapy treatment discovered

An urgent question for cancer scientists is why immunotherapy achieves dramatic results in some cases but doesn't help most patients. Now, two research groups from Dana-Farber Cancer Institute have independently discovered ...

Diseases, Conditions, Syndromes

New receptor 'decoy' drug neutralizes COVID-19 virus and its variants

Scientists at Dana-Farber Cancer Institute have developed a drug that potently neutralizes SARS-CoV-2, the COVID-19 coronavirus, and is equally effective against the Omicron variant and every other tested variant. The drug ...

page 2 from 37