Page 2 - European Molecular Biology Laboratory

Genetics

Large-scale study enables new insights into rare eye disorders

Researchers have analyzed image and genomic data from the UK Biobank to find insights into rare diseases of the human eye. These include retinal dystrophies—a group of inherited disorders affecting the retina—which are ...

Genetics

A human interactome to prioritize drug discovery

Scientists at Open Targets, EMBL's European Bioinformatics Institute (EMBL-EBI), and GSK are revealing the shared basis of diseases using a map of interacting human proteins. By helping to understand how biological processes ...

Medications

Combi-seq: A leap forward for personalized cancer therapy

Each year, around 10 million lives around the world are cut short by cancer. While the last century of research has seen the number of approved anticancer drugs grow by leaps and bounds, the sheer diversity of disease forms ...

Genetics

Genomic sequencing aids the global tuberculosis fight

The COVID-19 pandemic continues, but there is another global infectious disease that has a huge impact on the world. Tuberculosis (TB) causes over 1.5 million deaths and over 10 million infections per year. Estimates suggest ...

Medications

The impact of drugs on gut microbes is greater than we thought

We are one of the most medicated generations of humans to live on our planet. Cardiometabolic diseases like type 2 diabetes, obesity, and coronary artery disease continue to increase in prevalence and together constitute ...

Medications

Tackling the collateral damage from antibiotics

Antibiotics cure bacterial infections and save millions of lives each year. But they can also harm the helpful microbes residing in the gut, weakening one of the body's first lines of defense against pathogens and compromising ...

Diseases, Conditions, Syndromes

SARS-CoV-2 curtails immune response in the gut

In an effort to determine the potential for COVID-19 to begin in a person's gut, and to better understand how human cells respond to SARS-CoV-2, scientists at the European Molecular Biology Laboratory used human intestinal ...

HIV & AIDS

A new piece of the HIV infection puzzle explored

Scientists at EMBL Heidelberg and at the Zentrum für Infektiologie at Heidelberg University Hospital have succeeded for the first time in imaging HIV during transport into the nucleus of an infected cell. The electron tomographic ...

Medical research

Protein sequences provide clues to how SARS-CoV-2 infects cells

In the early days of the COVID-19 pandemic, it was established that SARS-CoV-2 infects cells by binding to the human protein ACE2, which plays a role in regulating blood pressure. But ACE2 is almost absent in human lung cells, ...

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