German Cancer Research Center

Oncology & Cancer

Epigenetically acting drugs could support cancer immunotherapy

Epigenetically active drugs enable the cell to read parts oft he genome that were previously blocked and inaccessible. This leads to the formation of new mRNA transcripts and also new proteins, as scientists from the German ...

Oncology & Cancer

Testing transgenic T cells against malignant brain tumors

Scientists from the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim (UMM) have successfully tested a new form of cellular immunotherapy against brain tumors in mice for the first time.

Genetics

Epigenetic profiling identifies potential COPD treatment targets

Impaired function of lung fibroblast is considered causative for symptoms of the incurable lung disease COPD (Chronic Obstructive Pulmonary Disease). Using high-resolution epigenetic profiling, German and British scientists ...

Oncology & Cancer

Study: B cells promote liver cancer with dangerous dual strategy

Inflammatory fatty liver disease (NASH, non alcoholic steatohepatitis) and the resulting liver cancer are driven by auto-aggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what is behind ...

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