Goethe University Frankfurt am Main

Medical research

Toxin responsible for Legionella growth identified

A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modification on human proteins and helps ...

Neuroscience

Surprising network activity in the immature brain

One of the outstanding mysteries of the cerebral cortex is how individual neurons develop the proper synaptic connections to form large-scale, distributed networks. Now, an international team of scientists including researchers ...

Neuroscience

Blood vessels instruct brain development

Function and homeostasis of the brain relies on communication between its complex network of cells. Consequently, development of the different groups of cells in the brain needs to be coordinated in time and space. The group ...

Oncology & Cancer

Why cancer cells grow despite a lack of oxygen

Healthy cells reduce their growth when there is a lack of oxygen (hypoxia). This makes it even more surprising that hypoxia is a characteristic feature of malignant tumours. In two publications in the current edition of the ...

Oncology & Cancer

mRNA therapeutic successfully combats ovarian cancer in mice

Each year, several thousand women in Germany die from ovarian cancer. In many cases, the disease is only detected when it is very advanced and metastases have already formed—usually in the intestines, abdomen or lymph nodes. ...

Oncology & Cancer

Examining the cause of leukemia in trisomy 21

Leukemia (blood cancer) is a group of malignant and aggressive diseases of the blood-forming cells in the bone marrow. Very intensive chemotherapy and in some cases a bone marrow transplant are the only cure. Like all cancers, ...

Health

Back pain: 84% increase in treatment success rate

If a therapy for chronic back pain is tailored specifically to a patient's individual requirements, the chances of success are far greater than with standard forms of treatment. Accompanied by a psychotherapeutic procedure ...

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