Helmholtz Association of German Research Centres

Diabetes

How does friendly fire happen in the pancreas?

In type 1 diabetes, the body attacks its own insulin-producing cells. Scientists at Helmholtz Zentrum München, partner in the German Center for Diabetes Research, and their colleagues at Technical University of Munich have ...

Oncology & Cancer

Molecularly shutting down cancer cachexia

Healthy fat tissue is essential for extended survival in the event of tumor-induced wasting syndrome (cachexia). In Nature Medicine, researchers at Helmholtz Zentrum München show that selective manipulation of an enzyme ...

Medical research

How fasting helps fight fatty liver disease

Scientists at Helmholtz Zentrum München have new information on what happens at the molecular level when we go hungry. Working with the Deutsches Zentrum für Diabetesforschung (German Center for Diabetes Research - DZD) ...

Diabetes

Metformin influences nitrogen and urea metabolism

The most frequently prescribed oral antidiabetic drug metformin significantly affects metabolic pathways. This was reported by scientists from the Helmholtz Zentrum München together with colleagues from the German Diabetes ...

Genetics

You are what your parents ate

Scientists at Helmholtz Zentrum München, in collaboration with researchers from Technical University of Munich and the German Center for Diabetes Research, have shown that diet-induced obesity and diabetes can be epigenetically ...

Medical research

Why the sense of smell declines in old age

As mammals age, their sense of smell deteriorates. In a study published in the journal Cell Reports, an interdisciplinary research team at Helmholtz Zentrum München and the University Medical Centre Mainz investigated why ...

Immunology

GI tract bacteria may protect against autoimmune disease

Early life exposure to normal bacteria of the GI tract (gut microbes) protects against autoimmune disease in mice, according to research published on-line in the January 17 edition of Science. The study may also have uncovered ...

Diabetes

Antibody affinity is decisive in Type 1 diabetes in adults

Patients with LADA – a form of autoimmune type 1 diabetes in adulthood – can be distinguished from patients with non-autoimmune type 2 diabetes by means of the antibody reaction affinity to the enzyme glutamic acid decarboxylase ...

Oncology & Cancer

Tapeworm drug inhibits colon cancer metastasis

A compound that for about 60 years has been used as a drug against tapeworm infection is also apparently effective against colon cancer metastasis, as studies using mice have now shown. The compound silences a gene that triggers ...

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