A recently published paper in the journal Molecular Cancer by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute, ICREA Research Professor and Genetics Chairman at the University ...
Feb 17, 2022
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In autoimmunity, the mechanisms that guarantee that our defense system does not attack our own body—tolerance to oneself—does not work properly. Multiple sclerosis, which affects one in every 1,000 people in Spain, is ...
Jan 19, 2022
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In the last few years, an alternative for these cases has emerged: a cell therapy known as CAR-T that collects the T-lymphocytes of these patients, modifies them through genetic engineering in the laboratory and administer ...
Oct 4, 2021
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Before the first oncogene mutations were discovered in human cancer in the early 1980s, the 1970s provided the first data suggesting alterations in the genetic material of tumors. In this context, the prestigious journal ...
Aug 12, 2020
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The Chromatin Biology group aims to define the mechanisms involved in the cellular response to different types of stress such as metabolic, oxidative and genotoxic stress. In particular, they focus on the impact of a family ...
Jul 27, 2020
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Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are a group of rare malignancies with overlapping features from myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN) that include a variety of diseases ...
Jul 1, 2020
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Acute myeloid leukemia (AML) is a hematological malignancy the incidence of which increases with age, that is biologically, phenotypically, and genetically very heterogeneous. Its treatment combines chemotherapy followed ...
Jun 17, 2020
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B-cell acute lymphoblastic leukemia (B-ALL) is characterized by the accumulation of abnormal immature B-cell precursors (BCP) in the bone marrow (BM), and is the most common pediatric cancer. Among the different subtypes ...
Apr 23, 2020
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The Cancer Genetics Group of the Josep Carreras Leukaemia Research Institute, led by Montse Sánchez-Céspedes, together with Luis Montuenga from CIMA, and Enriqueta Felip from Vall d'Hebron Hospital, has revealed that inactivation ...
Jan 23, 2020
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Acute myeloid leukemia is the most common type of leukemia in adults. It is characterized by the pathological expansion of immature cells (myeloblasts) that invade the bone marrow and expand into the blood, affecting the ...
Jan 2, 2020
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