Joslin Diabetes Center

Medical research

How important is the gut microbiome? It may depend on your genetics

Our gut microbiomes—the bacteria that live in our digestive tract—play major roles in our health. Scientists around the world are studying therapies that manipulate the microbiome, including probiotics (such as live bacterial ...

Diabetes

Finding new targets to treat vascular damage

Diabetes heightens the risk of vascular damage to heart and limbs, and impairs the ability to repair damage with new growth of blood vessels, called angiogenesis. There are no established drugs to improve angiogenesis in ...

Medical research

In cells, some oxidants are needed

Within our bodies, high levels of reactive forms of oxygen can damage proteins and contribute to diabetic complications and many other diseases. But some studies are showing that these reactive oxygen species (ROS) molecules ...

Medical research

Finding new clues to a sugar suspect in birth defects

Most pregnant women with well-controlled diabetes give birth to healthy children. But their babies run much higher risks of birth defects than babies born to women without diabetes, because very early in embryonic development, ...

Diabetes

Solving a genetic mystery in type 1 diabetes

In type 1 diabetes, the immune system attacks the body's own insulin-producing cells. Scientists understand reasonably well how this autoimmune attack progresses, but they don't understand what triggers the attack or how ...

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