Currently, few antimalarial treatments exist that effectively kill liver-stage malaria parasites, which can lay dormant for months or years as in the case of Plasmodium vivax. Researchers from Kanazawa University have successfully ...
Dec 12, 2018
0
0
In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes ...
Feb 15, 2023
0
48
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that can impair communication ability, socialization, and verbal and motor skills. It generally starts in early childhood and is diagnosed through behavior observation. ...
Oct 29, 2018
0
150
Systemic sclerosis (SSc, also known as scleroderma), a connective tissue disorder of autoimmune etiology, is characterized by excessive fibrosis in the skin and various internal organs. More than 90 percent of SSc patients ...
Aug 31, 2018
0
19
Severe inflammation in tissues is often associated with the occurrence of cancer. The mechanism linking both these conditions is not clearly understood. Furthermore, inflamed and cancerous tissues contain a heterogenous mix ...
Jan 25, 2019
0
42
The brain consists of neurons and glial cells. The developmental abnormality of glial cells causes various diseases and aberrant cerebral cortex development. CD38 gene knockout is shown to cause aberrant development of glial ...
Apr 7, 2017
0
2
In 1982, researchers reported a link between chronic gastritis and stomach bacterium Helicobacter pylori, triggering a flurry of research into this newly identified pathogen. These studies made it clear that in addition to ...
Apr 17, 2019
0
1
The brain's structure has columnar features, which are hypothesized to arise from nerve cells (neurons) stemming from the same parent cell, initially forming radial units. How exactly this process unfolds at the molecular ...
Sep 4, 2020
0
7
(Medical Xpress)—Researchers at Kanazawa University Graduate School of Medical Science in Japan have determined how APOBEC proteins mediate hypermutations that inhibit viral replication. They also identify the host factor ...
Jun 25, 2013
0
0
Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a membrane barrier that separates ...
Sep 15, 2023
0
50
