Ludwig Institute for Cancer Research

The Ludwig Institute for Cancer Research Ltd (LICR) is a global non-profit medical research institute that undertakes laboratory and clinical research into cancer, conducting and sponsoring its own early-phase clinical trials to investigate its discoveries. LICR is the largest international, non-profit institute dedicated to understanding and controlling cancer, with ~900 staff in seven countries across Australasia, Europe, and North and South America. There are currently nine LICR research Branches, which have a primary focus on basic laboratory and translational (in vivo and preclinical analyses of laboratory discoveries) sciences and are typically located within a university or research institute.

Website
http://www.licr.org/
Wikipedia
http://en.wikipedia.org/wiki/Ludwig_Institute_for_Cancer_Research

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Oncology & Cancer

Study shows how certain macrophages dampen anti-tumor immunity

A Ludwig Cancer Research study adds to growing evidence that immune cells known as macrophages inhabiting the body cavities that house our vital organs can aid tumor growth by distracting the immune system's cancer-killing ...

Oncology & Cancer

Study shows pancreatic cancer cells reverse to advance malignancy

A Ludwig Cancer Research study has identified a previously unrecognized mechanism by which cancer cells of a relatively benign subtype of pancreatic tumors methodically revert—or 'de-differentiate'—to a progenitor, or ...

Oncology & Cancer

Study reveals how certain gut bacteria compromise radiotherapy

A study led by Ludwig Chicago Co-director Ralph Weichselbaum and Yang-Xin Fu of the University of Texas Southwestern Medical Center has shown how bacteria in the gut can dull the efficacy of radiotherapy, a treatment received ...

Oncology & Cancer

A better test for the tumor-targeting of CAR-T therapies

Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies, in which the immune system's T cells are extracted from a ...

Oncology & Cancer

Study charts the immune landscape of multiple brain cancers

A Ludwig Cancer Research study has profiled, in a sweeping comparative analysis, the distinct immune landscapes of tumors that arise in the brain, or gliomas, and those that metastasize to the organ from the lungs, breast ...

Medical research

Study reveals bile metabolite of gut microbes boosts immune cells

A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells—immune cells that suppress autoimmune reactions and inflammation. ...

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