Ludwig Maximilian University of Munich

Genetics

Improved vectors for ocular gene therapy

Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development. Novel gene vectors now achieve widespread gene delivery and reduce the risks associated ...

Medical research

Functionality of immune cells in early life

A study by LMU researchers shows that putatively immature dendritic cells found in young children are able to induce robust immune responses. The results could lead to improved vaccination protocols.

Medical research

Coaxing cancer cells to commit suicide

An LMU team has identified an enzyme that is essential for DNA repair. Loss of this factor leads to cell death when cancer cells accumulate DNA damage. Chemical inhibition of the target protein offers a possible strategy ...

Medical research

An unconventional ion channel

Scientists at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified the first mechanosensitive ion channel to be found in an intracellular vesicle system. It responds to concentration changes within the vesicle, ...

Cardiology

How is the heartbeat regulated?

The heart can stably maintain blood flow—at rest or under stress—over a lifetime. Using a mouse model, an LMU team has now uncovered the role played by a specific class of ion channels in controlling the heart rate.

Diseases, Conditions, Syndromes

Study examines local perceptions of Chagas disease in Bolivia

A new study examines local perceptions of Chagas disease in a region where the infectious agent is endemic. The results underline the need to take social and cultural factors into account in campaigns designed to curb infectious ...

Medical research

The placebo effect meets the proteome

The molecular bases of the placebo effect are poorly understood. A team led by LMU researcher Karin Meissner has now studied the phenomenon in the context of nausea, and identified specific proteins that correlate with its ...

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