Ludwig Maximilian University of Munich

Medical research

Coaxing cancer cells to commit suicide

An LMU team has identified an enzyme that is essential for DNA repair. Loss of this factor leads to cell death when cancer cells accumulate DNA damage. Chemical inhibition of the target protein offers a possible strategy ...

Medical research

An unconventional ion channel

Scientists at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified the first mechanosensitive ion channel to be found in an intracellular vesicle system. It responds to concentration changes within the vesicle, ...

Cardiology

How is the heartbeat regulated?

The heart can stably maintain blood flow—at rest or under stress—over a lifetime. Using a mouse model, an LMU team has now uncovered the role played by a specific class of ion channels in controlling the heart rate.

Immunology

The immune system: Knocked off balance

Instead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune diseases and allergies. A Ludwig-Maximilian-Universitaet (LMU) in Munich team has dissected how mast cells regulate their calcium ...

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