Liver cancer is one of the most common cancer types worldwide and is especially common in China. A collaborative effort between researchers at the Netherlands Cancer Institute and Shanghai using CRISPR/Cas has led to the ...
Jul 21, 2021
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Tumor fragments in the lab are able to predict whether the corresponding real-life patients will benefit from immunotherapy. "We've solved a major problem many scientists had been facing: Preserving a tumor's original composition ...
Jul 8, 2021
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In their move to circumvent the immune system, melanoma cells end up with a deficiency of the crucial nutrient tryptophan. Unlike healthy cells, these cancer cells can continue to synthesize proteins to survive, but this ...
Dec 17, 2020
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In the scientific journal Nature Medicine, researchers in the Netherlands report that neoadjuvant immunotherapy using a combination of two drugs (nivolumab and ipilimumab) is a feasible treatment for bladder cancer without ...
Oct 19, 2020
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In Nature Medicine, the seven comprehensive cancer centers of Cancer Core Europe (CCE), including the Netherlands Cancer Institute and Cancer Research UK Cambridge center, have shared how they rapidly reorganised their oncological ...
Apr 17, 2020
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Patients with colon cancer but without distant metastases can benefit from a short course of immunotherapy while waiting for their surgery, as it can cause tumours to shrink substantially or clear up in a very short time. ...
Apr 6, 2020
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87
A classic boxing move, the "one-two punch," could also be effective against cancer: a left jab knocks cancer cells senseless, quickly followed by a right hook that knocks them out altogether. Researchers at the Netherlands ...
Oct 3, 2019
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Based on scientific findings of the Netherlands Cancer Institute, a new combination treatment has been developed for patients with metastatic bowel cancer and a mutation in the BRAF gene. After a clinical trial in over 600 ...
Sep 30, 2019
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Myeloid immune cells kill cancer cells by eating them but cancer cells prevent this from happening by giving out a 'do not eat me' signal. Led by immunologists Ton Schumacher (Netherlands Cancer Institute and Oncode) and ...
Mar 5, 2019
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113
Cancer cells that develop resistance to drugs pay a price for this by simultaneously developing a new vulnerability. If this acquired vulnerability can be identified, it may be exploited clinically. A team of cancer researchers, ...
May 10, 2018
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