Pacific Northwest National Laboratory

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An out-of-the-box attack on diabetes

A protein newly identified as important in type 1 diabetes can delay onset of the disease in diabetic mice, providing a new target for prevention and treatment in people, according to research led by scientists at the U.S. ...

Alzheimer's disease & dementia

The molecular mechanisms of Alzheimer's

Late-onset sporadic Alzheimer's disease (AD) accounts for about 99 percent of all cases, and is linked to multiple factors and pathogenetic mechanisms. One important contributor is a protein post-translational modification ...

Medical research

Profiling the gut microbiome proteins that modify bile

It turns out that bile is a lot more dynamic than you might think. One of the biggest factors affecting bile, which is very important to our ability to absorb nutrients, is our diet. But another is the make-up of the community ...

Medical research

Novel glimpses into early lung development

For most prematurely born infants, it's not their tiny size itself that makes life a struggle. Rather, it's the development of their lungs that spells the difference between life and death.

Medical research

Tackling infectious disease – one protein at a time

Garry Buchko and his colleagues are at the front line battling some of the most fearsome enemies that humanity has ever known: Tuberculosis. Pneumonia. Ebola. Plague. Botulism.

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