Perelman School of Medicine at the University of Pennsylvania

Oncology & Cancer

Novel drug shows early promise in treating multiple myeloma

A first-of-its-kind drug known as modakafusp alfa has shown early potential in combating multiple myeloma, a form of bone marrow cancer, in a study presented by researchers from the University of Pennsylvania's Abramson Cancer ...

Oncology & Cancer

Researchers present advance in re-treatment with CAR T therapy

Researchers from the University of Pennsylvania's Abramson Cancer Center presented preliminary results of an ongoing Phase I clinical trial demonstrating successful re-treatment with CAR T cell therapy for patients whose ...

Medications

Study shows promise of new anti-KRAS drug for pancreatic cancer

A small molecule inhibitor that attacks the difficult to target, cancer-causing gene mutation KRAS, found in nearly 30 percent of all human tumors, successfully shrunk tumors or stopped cancer growth in preclinical models ...

Medications

Study gives a peek at how ketamine acts as 'switch' in the brain

Ketamine, an established anesthetic and increasingly popular antidepressant, dramatically reorganizes activity in the brain, as if a switch had been flipped on its active circuits, according to a new study by Penn Medicine ...

Diseases, Conditions, Syndromes

CAR T cell therapy could reach beyond cancer

Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers. Now, investigators have reported highly promising early results for CAR T therapy in a small ...

page 7 from 40