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Neuroscience

Stopping the brain's memory circuits from overheating

The highly interconnected zones of the brain's hippocampus mediate spatial and episodic memory, but to keep memories organized they need the right balance of exciting and calming input. A part of the hippocampus called CA2 ...

Neuroscience

Finding real rewards in a virtual world

Researchers at the RIKEN Brain Science Institute have demonstrated that remembering where a goal is requires the same parts of the brain in virtual reality as it does in the real world. Published in the journal eNeuro, the ...

Genetics

Promising mouse model for a devastating genetic deficiency

Researchers from the RIKEN Global Research Cluster in Japan have developed a potential mouse model for the genetic disorder known as an NGLY1 deficiency. Published in the journal PLOS Genetics, the study describes how a complete ...

Diseases, Conditions, Syndromes

Sugar element of keratan sulfate halts the progress of emphysema

Using a mouse model, scientists from the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology and a number of other institutes have identified a sugar molecule that reduced the inflammatory response and progress ...

Medical research

Controlling the body clock

A new study from the laboratory of Hiroki Ueda at the RIKEN Quantitative Biology Center investigates circadian timekeeping with a novel approach to creating genetic knock-out rescue mice. Published in Molecular Cell, the ...

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