Seattle Children's Research Institute

Diseases, Conditions, Syndromes

New discovery paves way for next generation malaria vaccine

In an unprecedented first, scientists at Seattle Children's Research Institute have developed a genetically attenuated parasite (GAP) that arrests late in the liver stage of human malaria. Their findings published in JCI ...

Neuroscience

Light and genetic probes untangle dynamics of brain blood flow

While the human brain has over 400 miles of total vasculature, little is known about the tiny capillaries that make up much of this intricate labyrinth of blood vessels critical for delivering oxygenated blood and nutrients ...

Oncology & Cancer

Study helps parents build resilience to navigate child's cancer

Tatum Fettig remembers when her family's lives changed forever. In 2016, her daughter Teagan began vomiting and struggling with balance. At Seattle Children's, Teagan, then 2, was diagnosed with a pediatric brain tumor, medulloblastoma. ...

Oncology & Cancer

Solid tumors targeted in new CAR T-Cell immunotherapy trial

Seattle Children's has opened a chimeric antigen receptor (CAR) T-cell immunotherapy trial for children and young adults with relapsed or refractory non-central nervous system EGFR-expressing solid tumors. In the phase 1 ...

Immunology

Web-based tool helps parents improve on kids' asthma treatment

Asthma is the most common chronic illness in adolescents and children, affecting an estimated seven million children up to the age of 17 in the United States. The burden of asthma on children is substantial: kids with asthma ...

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