St. Jude Children's Research Hospital biologists have used engineered yeast cells to discover how a mutation that is frequently found in pediatric brain tumor high-grade glioma triggers a cascade of genomic malfunctions.
Jul 18, 2017
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About 11 percent of females who survive childhood cancer have an ovarian condition that leaves them at risk for infertility, weaker bones and frail health as young adults, according to research from St. Jude Children's Research ...
Jul 5, 2017
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A team from the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project (PCGP) has mapped the intricate changes in the "epigenetic" organization of the nucleus to determine how retinal ...
May 4, 2017
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Twelve percent of childhood cancer survivors carry germline mutations that put them or their children at increased risk of developing cancer, according to a landmark study presented today at the annual meeting of the American ...
Apr 3, 2017
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Researchers led by St. Jude Children's Research Hospital scientists have worked out how a crucial cancer-related protein, a "histone writer" called Ezh2, plays a role in suppressing as well as driving the most aggressive ...
Mar 21, 2017
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Childhood cancer survivors are living longer. Now research shows they are also less likely to develop second cancers while still young. The decline followed a sharp drop in the use of radiation therapy for treatment of childhood ...
Feb 28, 2017
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A high-risk subtype of acute lymphoblastic leukemia (ALL) first identified in children is highly prevalent in adults with ALL and is associated with a poor outcome, according to an international collaboration led by St. Jude ...
Nov 21, 2016
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Long-term survivors of childhood cancer live longer thanks to improvements to cancer treatments, but a new study looking at three decades of therapy suggests patients do not report better health status. The findings from ...
Nov 7, 2016
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Voluntary reporting by hospital staff of errors and patient safety events are a key source of information for improving patient care. A St. Jude Children's Research Hospital analysis suggests that to increase reporting, hospitals ...
Nov 1, 2016
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Revamping front-line multi-drug chemotherapy for retinoblastoma to include topotecan helped to maintain high cure rates for the eye cancer while preserving patients' vision and reducing their risk of treatment-related leukemia. ...
Oct 10, 2016
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