The Scripps Research Institute

The Scripps Research Institute (TSRI) is a biomedical research corporation established in La Jolla, California with another site in Jupiter, Florida. Its origins stem from a large endowment from Ellen Browning Scripps in the 1920s originally targeted for research on immune disorders. In the 1990s the combined Scripps Clinic and Research Institute became separate entitities. Today, TSRI is one of the most prolific and active research institutes in the United States with a wide range of human disorders/conditions in its focus. Namely, cancer biology, cell therapy, genetics, molecular and experimental medicine, neurobiology and more. The newly constructed Scripps Florida focuses on drug discoveries, basic biomedical research and technologies.

Address
10550 North Torrey Pines Road — La Jolla CA 92037 — US
Website
http://www.scripps.edu/e_index.html
Wikipedia
http://en.wikipedia.org/wiki/The_Scripps_Research_Institute

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Neuroscience

Unexplored neural circuit modulates memory strength

Learning to avoid negative experiences requires an interplay of two distinct brain circuits, one to interpret "Yikes!" and drive learning, and the other, unexpectedly, to dial in the strength of that memory, a new fruit fly ...

Neuroscience

Nanotubes enable travel of Huntington's protein

A toxic protein linked to Huntington's disease can move from neuron to neuron through a nanotube tunnel whose construction is initiated by a protein called Rhes, say scientists at Scripps Research.

Genetics

Gene repair improves memory and seizures in adult autism model

A new study challenges the presumption that people born with developmental brain disorders such as severe autism will benefit from medical interventions only if treated during a narrow window in infancy or early childhood.

Medical research

New therapy targets cause of adult-onset muscular dystrophy

People diagnosed with myotonic dystrophy type 1 have difficulty unclenching muscles due to a genetic defect that generates toxic material within their cells. There is currently no treatment. In a new report published in the ...

Parkinson's & Movement disorders

Scientists uncover how protein clumps damage cells in Parkinson's

Biologists studying Parkinson's disease have long hoped to solve the mystery of the telltale "clumps." Scientists want to know how clumps of misfolded proteins damage brain cells and contribute to the disease.

HIV & AIDS

HIV vaccine protects non-human primates from infection

For more than 20 years, scientists at Scripps Research have chipped away at the challenges of designing an HIV vaccine. Now new research, published in Immunity, shows that their experimental vaccine strategy works in non-human ...

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