Xylazine is an FDA-approved sedative and pain reliever for use in animals, but it has severe adverse effects when used in humans. It is now illicitly being added to opioids, like fentanyl and heroin, as well as cocaine—leading ...
Apr 3, 2024
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Scripps Research scientists have found that LY2444296—a compound that selectively blocks the kappa opioid receptor (KOP)—may reduce drinking in cases of alcohol dependence in animal studies. The findings, which were published ...
Mar 29, 2024
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Neuroscientists at Scripps Research have found that inhibiting neurons involved in the body's stress response may reduce alcohol consumption in people who have both post-traumatic stress disorder (PTSD) and alcohol use disorder ...
Mar 21, 2024
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Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells. In Alzheimer's disease, the ability to make energy is compromised, and the connections ...
Jan 29, 2024
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For decades, scientists have studied the intricate activity patterns in human and animal brains by observing when different groups of brain cells turn on. Equally important to understanding the brain and related diseases, ...
Jan 23, 2024
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Scientists from Scripps Research have developed a small molecule that blocks the activity of a protein linked to autoimmune diseases, including systemic lupus erythematosus (SLE) and Crohn's disease. This protein, known as ...
Jan 11, 2024
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Elucidating human contact networks could help predict and prevent the transmission of SARS-CoV-2 and future pandemic threats. A new study from Scripps Research scientists and collaborators points to which public health protocols ...
Dec 14, 2023
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A new artificial intelligence (AI) model designed by Scripps Research scientists could help clinicians better screen patients for atrial fibrillation (or AFib)—an irregular, fast heartbeat that is associated with stroke ...
Dec 12, 2023
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Neuroscientists at Scripps Research have identified brain circuits that make mammals want to eat more when they are exposed to cold temperatures.
Aug 16, 2023
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An antibody in single-chain fragment variable (scFv) format that binds to the powerful opioid carfentanil was shown to reverse signs of carfentanil overdose in preclinical tests conducted by scientists at Scripps Research.
Aug 7, 2023
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