Thomas Jefferson University

Oncology & Cancer

Nuclear gatekeeper could block undruggable prostate cancer targets

Certain molecular drivers of cancer growth are "undruggable—it's been nearly impossible to develop chemicals that would block their action and prevent cancer growth. Many of these molecules function by passing cancer-promoting ...

Neuroscience

What learning looks like in the brain

When we learn the connections between neurons strengthen. Addiction or other neurological diseases are linked to abnormally strong connections. But what does learning look like on the cellular and molecular level? How do ...

Neuroscience

Researchers identify new target for chronic pain

Proteins must be in the right place at the right time in the cell to function correctly. This is even more critical in a neuron than in other cells because of its complex tree-like structure and its function. Researchers ...

Oncology & Cancer

Targeting breast cancer metabolism to fight the disease

How does a cancer cell burn calories? New research from Thomas Jefferson University shows that breast cancer cells rely on a different process for turning fuel into energy than normal cells. The results were recently published ...

Immunology

New approach tests the strength of immunity

The immune system orchestrates large and small scale attacks on innumerous targets: viruses, bacteria, cancer, but it also misfires causing allergy or autoimmune reactions. Compounding the problem, not every immune reaction ...

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