A notable characteristic of several neurodegenerative diseases, such as Alzheimer's and Parkinson's, is the formation of harmful plaques that contain aggregates—also known as fibrils—of amyloid proteins. Unfortunately, ...
Aug 4, 2020
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In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs. This type of immune therapy is also used for cancer treatment, owing to the ...
Jul 21, 2020
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1
Alzheimer's disease is a progressive disorder in which the nerve cells (neurons) in a person's brain and the connections among them degenerate slowly, causing severe memory loss, intellectual deficiencies, and deterioration ...
Jul 20, 2020
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Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones. But the intracellular mechanisms through which macrophages ...
Jun 10, 2020
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Anxiety disorders such as phobias and PTSD are fairly common problems in society. One of the prime causes of anxiety disorders is the inability to overcome the fear for certain contexts when they no longer apply. Attempts ...
Feb 18, 2020
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Developing a therapy to combat cancer remains one of the most difficult challenges in medical research. Cancer cells use the host's own immune system to grow and spread, ultimately becoming deadly. Immune cells like macrophages, ...
Jan 30, 2020
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Autoimmune diseases are a medical conundrum. In people with these conditions, the immune system of the body, the designated defense system, starts attacking the cells or organs of its own body, mistaking internal cells for ...
Dec 18, 2019
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1
Immunodeficiency occurs when the capability of the immune system to fight against diseases has been compromised. Immunocompromised people have a higher chance of contracting diseases compared to people with healthy immune ...
Sep 26, 2019
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1
Active mutations of a certain signaling receptor protein called KIT tyrosine kinase are found in several cancers, such as acute myeloid leukemia (AML). However, the different locations in the AML cells where KIT induces cancer-specific ...
Sep 24, 2019
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1
Amyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are known to be a cause of several diseases—including Alzheimer's—and therefore, it ...
Aug 8, 2019
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