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Medical research

Study discovers molecular control hub for skin inflammation

Inflammatory reactions in the skin can reduce damage from UV radiation or infections, but can also result in painful symptoms such as sunburn. A recent study at the University of Bonn and the University Hospital Bonn has ...

Diseases, Conditions, Syndromes

Hemophilia: Training the immune system to be tolerant

Hemophilia A is the most common severe form of hemophilia. It almost exclusively affects males. The disease can usually be treated well, but not for all sufferers. A study at the University of Bonn has now elucidated an important ...

Neuroscience

Secret structure in the wiring diagram of the brain

In the brain, our perception arises from a complex interplay of neurons that are connected via synapses. But the number and strength of connections between certain types of neurons can vary. Researchers from the University ...

Ophthalmology

New diagnostic option for rare eye disease

An estimated 5 to 10% of blindness worldwide is caused by the rare inflammatory eye disease uveitis. Posterior uveitis in particular is often associated with severe disease progression and the need for immunosuppressive therapy. ...

Oncology & Cancer

Ceritinib offers a promising target for cancer immunotherapy

Many tumor cells mist themselves with a protective perfume that disables the immune system. But a drug already approved for other purposes can apparently render this weapon harmless. This is shown in a study by the University ...

Cardiology

Mechanism discovered that leads to ANCA-associated vasculitis

The immune system can become the enemy when mechanisms that are actually protective get out of control. In ANCA-associated vasculitis, excessive inflammatory reactions lead to pulmonary hemorrhages that can be fatal if left ...

Neuroscience

Timing of neuron development determines what they can become

When it comes to royalty, things are clear: The monarch's first child inherits the crown. Siblings born later must make do with a less glamorous profession. This is quite similar for some nerve cells in the brain. In their ...

Diseases, Conditions, Syndromes

COVID-19: New energy for flagging immune cells

In severe COVID-19 patients, metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order ...

Overweight & Obesity

Molecule boosts fat burning

Normally, fat cells store energy. In brown fat cells, however, energy is dissipated as heat—brown fat thus serves as a biological heater. Most mammals therefore have this mechanism. In humans it keeps newborns warm; in ...

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