University of California - San Diego

Neuroscience

Gene therapy approach shows promise in treating ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord responsible for voluntary movements and muscle control.

Diseases, Conditions, Syndromes

Iron buildup in brain linked to higher risk for movement disorders

A disorder called hereditary hemochromatosis, caused by a gene mutation, results in the body absorbing too much iron, leading to tissue damage and conditions like liver disease, heart problems and diabetes. Scant and conflicting ...

Gerontology & Geriatrics

Biological age, not birthdate may reveal healthy longevity

A first-of-its-kind study of 1,813 older women suggests that the accelerated biological aging of the body—epigenetic age acceleration specifically—is associated with lower odds of living to be 90 years old and also being ...

Immunology

A novel COVID-19 vaccine using modified bacterial DNA

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, describe a different way to build a COVID-19 vaccine, one that would, in theory, remain effective against new and emerging variants ...

Arthritis & Rheumatism

How mitochondrial damage ignites the 'auto-inflammatory fire'

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and ...

Psychology & Psychiatry

Mindfulness meditation reduces pain by separating it from the self

For centuries, people have been using mindfulness meditation to try to relieve their pain, but neuroscientists have only recently been able to test if and how this actually works. In the latest of these efforts, researchers ...

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