University of Pennsylvania

Diseases, Conditions, Syndromes

COVID mortality age patterns changed significantly during pandemic

Early in the pandemic, older populations in the United States suffered the greatest death toll from COVID-19. But Penn demographers Irma Elo and Samuel Preston, with Boston University's Andrew Stokes and others, wanted to ...

Immunology

How one inflammatory disorder exacerbates another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, ...

Immunology

Regulating the regulators of the immune system

Checkpoint inhibitors have become important tools in the cancer-fighting arsenal. By blocking proteins that normally restrain the immune response, these drugs can help the immune system destroy cancer cells.

Medications

Providing naloxone in the emergency department can save lives

Overdose deaths continue to be a national tragedy. More than 800,000 Americans died from an overdose between 1999–2019, and the annual rate of overdoses has increased dramatically during the pandemic, according to the latest ...

Diseases, Conditions, Syndromes

New insight into how atopic dermatitis develops

Atopic dermatitis, a common skin condition affecting both children and adults, is often thought of as an inflammatory disease that arises from a breakdown in the barrier function of the skin. Now a new study pinpoints a cascade ...

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