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Obstetrics & gynaecology

Drop race adjustment for AFP prenatal testing, study urges

A race-based adjustment to test-result values from a common prenatal screening should be discontinued, according to a study published this week in Obstetrics and Gynecology. The adjustment has historically been applied only ...

Diseases, Conditions, Syndromes

Genomic methods aid study of Seattle 2017-2022 Shigella outbreak

A genomic study of a sustained, multidrug-resistant Shigellosis outbreak in Seattle enabled scientists to retrace its origin and spread. Additional analysis of the gut pathogen and its transmission patterns helped direct ...

Immunology

How regulatory T cells halt aberrant, self-reactive T cells

New research findings show in detail how self-reactive T cells—white blood cells that mistakenly attack healthy instead of infected cells, thereby causing an autoimmune or an inflammatory response—are held in check by ...

Medical research

Study illuminates sugar's role in common kidney disease

A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide.

Neuroscience

Targeting tau, the other protein behind Alzheimer's disease

In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to ...

Diseases, Conditions, Syndromes

New insights on antibody responses to omicron variants

Knowing how well vaccination against one SARS-Co-V2 strain (with or without previous infection) counteracts infection with a different strain is a critical research question. The answers could guide strategies to continue ...

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