Whitehead Institute for Biomedical Research

Oncology & Cancer

Tracing a cancer's family tree to its roots reveals how tumors grow

Over time, cancer cells can evolve to become resistant to treatment, more aggressive, and metastatic—capable of spreading to additional sites in the body and forming new tumors. The more of these traits that a cancer evolves, ...

Genetics

Opioids and the brain: New insights through epigenetics

Drug overdose, mostly from opioid use, is the leading cause of accidental death in the United States. Prior studies of twins have revealed that genetics play a key role in opioid use disorder. Researchers know that a mixture ...

Medical research

Type 1 diabetes from a beta cell's perspective

Type 1 diabetes is an autoimmune disease that occurs when T-cells in the immune system attack the body's own insulin-producing cells, called beta cells, in the pancreas. Usually diagnosed in children and young adults, type ...

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