Neuroscience

Research reveals drug targets for memory enhancement

Bristol-led research has identified specific drug targets within the neural circuits that encode memories, paving the way for significant advances in the treatment of a broad spectrum of brain disorders.

Medications

Common Alzheimer's treatment linked to slower cognitive decline

Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer's disease, but their effects on cognition have been debated and few studies have investigated their long-term effects. A new study ...

Neuroscience

How the brain makes sense of touch

EPFL researchers have identified specific neurons that help activate sensory processing in nearby nerve cells—a finding that could explain how the brain integrates signals necessary for tactile perception and learning.

Medical research

Newly discovered mechanism can explain increased risk of dementia

Millions of people around the world use proton pump inhibitors for conditions like heartburn, gastritis and stomach ulcers. Researchers at Karolinska Institutet in Sweden now report that the long-term use of these drugs could ...

Neuroscience

Researchers find key to keep working memory working

Working memory, the ability to hold a thought in mind even through distraction, is the foundation of abstract reasoning and a defining characteristic of the human brain. It is also impaired in disorders such as schizophrenia ...

Oncology & Cancer

Scientists 'get on the nerves' of cancer cells

Modulation of neuroreceptors can stop the growth of lung carcinoma (cancer) cells, according to a recent study conducted by a group of researchers from the Institute of Bioorganic Chemistry of the Russian Academy of Sciences ...

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Acetylcholine

The chemical compound acetylcholine (often abbreviated ACh) is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans. Acetylcholine is one of many neurotransmitters in the autonomic nervous system (ANS) and the only neurotransmitter used in the motor division of the somatic nervous system (sensory neurons use glutamate and various peptides at their synapses). Acetylcholine is also the principal neurotransmitter in all autonomic ganglia.

Acetylcholine slows the heart rate when functioning as an inhibitory neurotransmitter. However, acetylcholine also behaves as an excitatory neurotransmitter at neuromuscular junctions.

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